Widman DG - Search Results

1

Functional Transplant of a Dengue Virus Serotype 3 (DENV3)-Specific Human Monoclonal Antibody Epitope into DENV1.

Messer WB, Yount BL, Royal SR, de Alwis R, Widman DG, Smith SA, Crowe JE Jr, Pfaff JM, Kahle KM, Doranz BJ, Ibarra KD, Harris E, de Silva AM, Baric RS. Messer WB, et al. Among authors: widman dg. J Virol. 2016 Apr 29;90(10):5090-5097. doi: 10.1128/JVI.00155-16. Print 2016 May 15. J Virol. 2016. PMID: 26962223 Free PMC article.

2

Mapping the Human Memory B Cell and Serum Neutralizing Antibody Responses to Dengue Virus Serotype 4 Infection and Vaccination.

Nivarthi UK, Kose N, Sapparapu G, Widman D, Gallichotte E, Pfaff JM, Doranz BJ, Weiskopf D, Sette A, Durbin AP, Whitehead SS, Baric R, Crowe JE Jr, de Silva AM. Nivarthi UK, et al. J Virol. 2017 Feb 14;91(5):e02041-16. doi: 10.1128/JVI.02041-16. Print 2017 Mar 1. J Virol. 2017. PMID: 28031369 Free PMC article.

3

Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model.

Callaway JB, Smith SA, Widman DG, McKinnon KP, Scholle F, Sempowski GD, Dittmer DP, Crowe JE Jr, de Silva AM, Ting JP. Callaway JB, et al. Among authors: widman dg. PLoS One. 2015 Aug 24;10(8):e0136708. doi: 10.1371/journal.pone.0136708. eCollection 2015. PLoS One. 2015. PMID: 26301593 Free PMC article.

4

Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone.

Gallichotte EN, Menachery VD, Yount BL Jr, Widman DG, Dinnon KH 3rd, Hartman S, de Silva AM, Baric RS. Gallichotte EN, et al. Among authors: widman dg. mSphere. 2017 Feb 22;2(1):e00380-16. doi: 10.1128/mSphere.00380-16. eCollection 2017 Jan-Feb. mSphere. 2017. PMID: 28251184 Free PMC article.

5

Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3 into serotype 4.

Widman DG, Young E, Nivarthi U, Swanstrom JA, Royal SR, Yount BL, Debbink K, Begley M, Marcet S, Durbin A, de Silva AM, Messer WB, Baric RS. Widman DG, et al. Sci Rep. 2017 Dec 7;7(1):17169. doi: 10.1038/s41598-017-17355-5. Sci Rep. 2017. PMID: 29215033 Free PMC article.

6

Human dengue virus serotype 2 neutralizing antibodies target two distinct quaternary epitopes.

Gallichotte EN, Baric TJ, Yount BL Jr, Widman DG, Durbin A, Whitehead S, Baric RS, de Silva AM. Gallichotte EN, et al. Among authors: widman dg. PLoS Pathog. 2018 Feb 26;14(2):e1006934. doi: 10.1371/journal.ppat.1006934. eCollection 2018 Feb. PLoS Pathog. 2018. PMID: 29481552 Free PMC article.

7

Analyzing the Human Serum Antibody Responses to a Live Attenuated Tetravalent Dengue Vaccine Candidate.

Swanstrom JA, Henein S, Plante JA, Yount BL, Widman DG, Gallichotte EN, Dean HJ, Osorio JE, Partidos CD, de Silva AM, Baric RS. Swanstrom JA, et al. Among authors: widman dg. J Infect Dis. 2018 May 25;217(12):1932-1941. doi: 10.1093/infdis/jiy063. J Infect Dis. 2018. PMID: 29800370 Free PMC article. Clinical Trial.

8

Genetic Variation between Dengue Virus Type 4 Strains Impacts Human Antibody Binding and Neutralization.

Gallichotte EN, Baric TJ, Nivarthi U, Delacruz MJ, Graham R, Widman DG, Yount BL, Durbin AP, Whitehead SS, de Silva AM, Baric RS. Gallichotte EN, et al. Among authors: widman dg. Cell Rep. 2018 Oct 30;25(5):1214-1224. doi: 10.1016/j.celrep.2018.10.006. Cell Rep. 2018. PMID: 30380413 Free PMC article.

9

Beyond Neutralizing Antibody Levels: The Epitope Specificity of Antibodies Induced by National Institutes of Health Monovalent Dengue Virus Vaccines.

Swanstrom JA, Nivarthi UK, Patel B, Delacruz MJ, Yount B, Widman DG, Durbin AP, Whitehead SS, De Silva AM, Baric RS. Swanstrom JA, et al. Among authors: widman dg. J Infect Dis. 2019 Jun 19;220(2):219-227. doi: 10.1093/infdis/jiz109. J Infect Dis. 2019. PMID: 30895307 Free PMC article.

10

Dengue virus envelope protein domain I/II hinge: a key target for dengue virus vaccine design?

Widman DG, Baric RS. Widman DG, et al. Expert Rev Vaccines. 2015 Jan;14(1):5-8. doi: 10.1586/14760584.2015.961431. Epub 2014 Sep 24. Expert Rev Vaccines. 2015. PMID: 25249440

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