Gough DJ - Search Results

1

The JAK/STAT pathway in obesity and diabetes.

Gurzov EN, Stanley WJ, Pappas EG, Thomas HE, Gough DJ. Gurzov EN, et al. Among authors: gough dj. FEBS J. 2016 Aug;283(16):3002-15. doi: 10.1111/febs.13709. Epub 2016 Apr 1. FEBS J. 2016. PMID: 26972840 Free article. Review.

2

JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity.

Litwak SA, Pang L, Galic S, Igoillo-Esteve M, Stanley WJ, Turatsinze JV, Loh K, Thomas HE, Sharma A, Trepo E, Moreno C, Gough DJ, Eizirik DL, de Haan JB, Gurzov EN. Litwak SA, et al. Among authors: gough dj. Diabetes. 2017 Dec;66(12):2973-2986. doi: 10.2337/db17-0348. Epub 2017 Sep 19. Diabetes. 2017. PMID: 28928277

3

STAT3 Regulates Mitochondrial Gene Expression in Pancreatic β-Cells and Its Deficiency Induces Glucose Intolerance in Obesity.

Schaschkow A, Pang L, Vandenbempt V, Elvira B, Litwak SA, Vekeriotaite B, Maillard E, Vermeersch M, Paula FMM, Pinget M, Perez-Morga D, Gough DJ, Gurzov EN. Schaschkow A, et al. Among authors: gough dj. Diabetes. 2021 Sep;70(9):2026-2041. doi: 10.2337/db20-1222. Epub 2021 Jun 28. Diabetes. 2021. PMID: 34183374

4

Mitochondrial STAT3: Powering up a potent factor.

Garama DJ, White CL, Balic JJ, Gough DJ. Garama DJ, et al. Among authors: gough dj. Cytokine. 2016 Nov;87:20-5. doi: 10.1016/j.cyto.2016.05.019. Epub 2016 Jun 3. Cytokine. 2016. PMID: 27269970 Review.

5

Therapeutically exploiting STAT3 activity in cancer - using tissue repair as a road map.

Huynh J, Chand A, Gough D, Ernst M. Huynh J, et al. Nat Rev Cancer. 2019 Feb;19(2):82-96. doi: 10.1038/s41568-018-0090-8. Nat Rev Cancer. 2019. PMID: 30578415 Review.

6

A novel c-Jun-dependent signal transduction pathway necessary for the transcriptional activation of interferon gamma response genes.

Gough DJ, Sabapathy K, Ko EY, Arthur HA, Schreiber RD, Trapani JA, Clarke CJ, Johnstone RW. Gough DJ, et al. J Biol Chem. 2007 Jan 12;282(2):938-46. doi: 10.1074/jbc.M607674200. Epub 2006 Nov 14. J Biol Chem. 2007. PMID: 17105733 Free article.

7

IFNgamma signaling-does it mean JAK-STAT?

Gough DJ, Levy DE, Johnstone RW, Clarke CJ. Gough DJ, et al. Cytokine Growth Factor Rev. 2008 Oct-Dec;19(5-6):383-94. doi: 10.1016/j.cytogfr.2008.08.004. Epub 2008 Oct 16. Cytokine Growth Factor Rev. 2008. PMID: 18929502 Review.

8

STAT3: a multifaceted oncoprotein.

Guanizo AC, Fernando CD, Garama DJ, Gough DJ. Guanizo AC, et al. Among authors: gough dj. Growth Factors. 2018 Apr;36(1-2):1-14. doi: 10.1080/08977194.2018.1473393. Epub 2018 Jun 6. Growth Factors. 2018. PMID: 29873274 Review.

9

Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2.

Liu YD, Yu L, Ying L, Balic J, Gao H, Deng NT, West A, Yan F, Ji CB, Gough D, Tan P, Jenkins BJ, Li JK. Liu YD, et al. Int J Cancer. 2019 Jun 15;144(12):3056-3069. doi: 10.1002/ijc.32060. Epub 2019 Jan 7. Int J Cancer. 2019. PMID: 30536754 Free PMC article.

10

Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling.

Cochrane CR, Vaghjiani V, Szczepny A, Jayasekara WSN, Gonzalez-Rajal A, Kikuchi K, McCaughan GW, Burgess A, Gough DJ, Watkins DN, Cain JE. Cochrane CR, et al. Among authors: gough dj. J Clin Invest. 2020 Aug 3;130(8):4006-4018. doi: 10.1172/JCI132513. J Clin Invest. 2020. PMID: 32568216 Free PMC article.

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