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Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74.
J Virol. 2016 May 27;90(12):5808-5823. doi: 10.1128/JVI.03116-15. Print 2016 Jun 15.
J Virol. 2016.
PMID: 27076642
Free PMC article.
Compensatory substitutions in the HIV-1 capsid reduce the fitness cost associated with resistance to a capsid-targeting small-molecule inhibitor.
Shi J, Zhou J, Halambage UD, Shah VB, Burse MJ, Wu H, Blair WS, Butler SL, Aiken C.
Shi J, et al. Among authors: halambage ud.
J Virol. 2015 Jan;89(1):208-19. doi: 10.1128/JVI.01411-14. Epub 2014 Oct 15.
J Virol. 2015.
PMID: 25320302
Free PMC article.
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HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry.
Zhou J, Price AJ, Halambage UD, James LC, Aiken C.
Zhou J, et al. Among authors: halambage ud.
J Virol. 2015 Sep;89(17):9068-79. doi: 10.1128/JVI.00340-15. Epub 2015 Jun 24.
J Virol. 2015.
PMID: 26109731
Free PMC article.
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Inhibition of HIV-1 Maturation via Small-Molecule Targeting of the Amino-Terminal Domain in the Viral Capsid Protein.
Wang W, Zhou J, Halambage UD, Jurado KA, Jamin AV, Wang Y, Engelman AN, Aiken C.
Wang W, et al. Among authors: halambage ud.
J Virol. 2017 Apr 13;91(9):e02155-16. doi: 10.1128/JVI.02155-16. Print 2017 May 1.
J Virol. 2017.
PMID: 28202766
Free PMC article.
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A Novel Phenotype Links HIV-1 Capsid Stability to cGAS-Mediated DNA Sensing.
Siddiqui MA, Saito A, Halambage UD, Ferhadian D, Fischer DK, Francis AC, Melikyan GB, Ambrose Z, Aiken C, Yamashita M.
Siddiqui MA, et al. Among authors: halambage ud.
J Virol. 2019 Jul 30;93(16):e00706-19. doi: 10.1128/JVI.00706-19. Print 2019 Aug 15.
J Virol. 2019.
PMID: 31167922
Free PMC article.
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Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.
Price AJ, Jacques DA, McEwan WA, Fletcher AJ, Essig S, Chin JW, Halambage UD, Aiken C, James LC.
Price AJ, et al. Among authors: halambage ud.
PLoS Pathog. 2014 Oct 30;10(10):e1004459. doi: 10.1371/journal.ppat.1004459. eCollection 2014 Oct.
PLoS Pathog. 2014.
PMID: 25356722
Free PMC article.
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Microplate-based assay for identifying small molecules that bind a specific intersubunit interface within the assembled HIV-1 capsid.
Halambage UD, Wong JP, Melancon BJ, Lindsley CW, Aiken C.
Halambage UD, et al.
Antimicrob Agents Chemother. 2015 Sep;59(9):5190-5. doi: 10.1128/AAC.00646-15. Epub 2015 Jun 15.
Antimicrob Agents Chemother. 2015.
PMID: 26077250
Free PMC article.
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