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Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.
Jönsson P, Southcombe JH, Santos AM, Huo J, Fernandes RA, McColl J, Lever M, Evans EJ, Hudson A, Chang VT, Hanke T, Godkin A, Dunne PD, Horrocks MH, Palayret M, Screaton GR, Petersen J, Rossjohn J, Fugger L, Dushek O, Xu XN, Davis SJ, Klenerman D. Jönsson P, et al. Among authors: dushek o. Proc Natl Acad Sci U S A. 2016 May 17;113(20):5682-7. doi: 10.1073/pnas.1513918113. Epub 2016 Apr 25. Proc Natl Acad Sci U S A. 2016. PMID: 27114505 Free PMC article.
Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation.
Salio M, Ghadbane H, Dushek O, Shepherd D, Cypen J, Gileadi U, Aichinger MC, Napolitani G, Qi X, van der Merwe PA, Wojno J, Veerapen N, Cox LR, Besra GS, Yuan W, Cresswell P, Cerundolo V. Salio M, et al. Among authors: dushek o. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):E4753-61. doi: 10.1073/pnas.1310050110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248359 Free PMC article.
SpyAvidin hubs enable precise and ultrastable orthogonal nanoassembly.
Fairhead M, Veggiani G, Lever M, Yan J, Mesner D, Robinson CV, Dushek O, van der Merwe PA, Howarth M. Fairhead M, et al. Among authors: dushek o. J Am Chem Soc. 2014 Sep 3;136(35):12355-63. doi: 10.1021/ja505584f. Epub 2014 Aug 21. J Am Chem Soc. 2014. PMID: 25111182 Free PMC article.
Phenotypic models of T cell activation.
Lever M, Maini PK, van der Merwe PA, Dushek O. Lever M, et al. Among authors: dushek o. Nat Rev Immunol. 2014 Sep;14(9):619-29. doi: 10.1038/nri3728. Nat Rev Immunol. 2014. PMID: 25145757 Free article. Review.
65 results