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Page 1
Alzheimer's disease.
Masters CL, Bateman R, Blennow K, Rowe CC, Sperling RA, Cummings JL. Masters CL, et al. Among authors: bateman r. Nat Rev Dis Primers. 2015 Oct 15;1:15056. doi: 10.1038/nrdp.2015.56. Nat Rev Dis Primers. 2015. PMID: 27188934 Free article. Review.
Decreased clearance of CNS beta-amyloid in Alzheimer's disease.
Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, Morris JC, Yarasheski KE, Bateman RJ. Mawuenyega KG, et al. Science. 2010 Dec 24;330(6012):1774. doi: 10.1126/science.1197623. Epub 2010 Dec 9. Science. 2010. PMID: 21148344 Free PMC article.
Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction.
Hata S, Fujishige S, Araki Y, Taniguchi M, Urakami K, Peskind E, Akatsu H, Araseki M, Yamamoto K, Martins RN, Maeda M, Nishimura M, Levey A, Chung KA, Montine T, Leverenz J, Fagan A, Goate A, Bateman R, Holtzman DM, Yamamoto T, Nakaya T, Gandy S, Suzuki T. Hata S, et al. Among authors: bateman r. Ann Neurol. 2011 Jun;69(6):1026-31. doi: 10.1002/ana.22343. Ann Neurol. 2011. PMID: 21681798 Free PMC article.
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.
Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM. Castellano JM, et al. Among authors: bateman rj. Sci Transl Med. 2011 Jun 29;3(89):89ra57. doi: 10.1126/scitranslmed.3002156. Sci Transl Med. 2011. PMID: 21715678 Free PMC article.
Alzheimer's disease therapeutic trials: EU/US Task Force report on recruitment, retention, and methodology.
Vellas B, Hampel H, Rougé-Bugat ME, Grundman M, Andrieu S, Abu-Shakra S, Bateman R, Berman R, Black R, Carrillo M, Donohue M, Mintun M, Morris J, Petersen R, Thomas RG, Suhy J, Schneider L, Seely L, Tariot P, Touchon J, Weiner M, Sampaio C, Aisen P; Task Force Participants. Vellas B, et al. Among authors: bateman r. J Nutr Health Aging. 2012 Apr;16(4):339-45. doi: 10.1007/s12603-012-0044-x. J Nutr Health Aging. 2012. PMID: 22499454 Free article.
Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer's disease.
Portelius E, Zetterberg H, Dean RA, Marcil A, Bourgeois P, Nutu M, Andreasson U, Siemers E, Mawuenyega KG, Sigurdson WC, May PC, Paul SM, Holtzman DM, Blennow K, Bateman RJ. Portelius E, et al. J Alzheimers Dis. 2012;31(2):335-41. doi: 10.3233/JAD-2012-120508. J Alzheimers Dis. 2012. PMID: 22531418 Free PMC article. Clinical Trial.
Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer's disease subjects.
Hata S, Taniguchi M, Piao Y, Ikeuchi T, Fagan AM, Holtzman DM, Bateman R, Sohrabi HR, Martins RN, Gandy S, Urakami K, Suzuki T; Japanese Alzheimer's Disease Neuroimaging Initiative. Hata S, et al. Among authors: bateman r. Mol Neurodegener. 2012 Apr 25;7:16. doi: 10.1186/1750-1326-7-16. Mol Neurodegener. 2012. PMID: 22534039 Free PMC article.
539 results