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Atrasentan Reduces Albuminuria by Restoring the Glomerular Endothelial Glycocalyx Barrier in Diabetic Nephropathy.
Boels MG, Avramut MC, Koudijs A, Dane MJ, Lee DH, van der Vlag J, Koster AJ, van Zonneveld AJ, van Faassen E, Gröne HJ, van den Berg BM, Rabelink TJ. Boels MG, et al. Among authors: van der vlag j, van zonneveld aj, van faassen e, van den berg bm. Diabetes. 2016 Aug;65(8):2429-39. doi: 10.2337/db15-1413. Epub 2016 Mar 25. Diabetes. 2016. PMID: 27207530
Increased expression of heparanase in overt diabetic nephropathy.
van den Hoven MJ, Rops AL, Bakker MA, Aten J, Rutjes N, Roestenberg P, Goldschmeding R, Zcharia E, Vlodavsky I, van der Vlag J, Berden JH. van den Hoven MJ, et al. Among authors: van der vlag j. Kidney Int. 2006 Dec;70(12):2100-8. doi: 10.1038/sj.ki.5001985. Epub 2006 Oct 18. Kidney Int. 2006. PMID: 17051139 Free article.
Heparanase is essential for the development of diabetic nephropathy in mice.
Gil N, Goldberg R, Neuman T, Garsen M, Zcharia E, Rubinstein AM, van Kuppevelt T, Meirovitz A, Pisano C, Li JP, van der Vlag J, Vlodavsky I, Elkin M. Gil N, et al. Among authors: van kuppevelt t, van der vlag j. Diabetes. 2012 Jan;61(1):208-16. doi: 10.2337/db11-1024. Epub 2011 Nov 21. Diabetes. 2012. PMID: 22106160 Free PMC article.
Glomerular endothelial surface layer acts as a barrier against albumin filtration.
Dane MJ, van den Berg BM, Avramut MC, Faas FG, van der Vlag J, Rops AL, Ravelli RB, Koster BJ, van Zonneveld AJ, Vink H, Rabelink TJ. Dane MJ, et al. Among authors: van der vlag j, van zonneveld aj, van den berg bm. Am J Pathol. 2013 May;182(5):1532-40. doi: 10.1016/j.ajpath.2013.01.049. Epub 2013 Mar 19. Am J Pathol. 2013. PMID: 23518410
Association of kidney function with changes in the endothelial surface layer.
Dane MJ, Khairoun M, Lee DH, van den Berg BM, Eskens BJ, Boels MG, van Teeffelen JW, Rops AL, van der Vlag J, van Zonneveld AJ, Reinders ME, Vink H, Rabelink TJ. Dane MJ, et al. Among authors: van der vlag j, van teeffelen jw, van zonneveld aj, van den berg bm. Clin J Am Soc Nephrol. 2014 Apr;9(4):698-704. doi: 10.2215/CJN.08160813. Epub 2014 Jan 23. Clin J Am Soc Nephrol. 2014. PMID: 24458084 Free PMC article.
Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis.
Rops AL, Loeven MA, van Gemst JJ, Eversen I, Van Wijk XM, Dijkman HB, van Kuppevelt TH, Berden JH, Rabelink TJ, Esko JD, van der Vlag J. Rops AL, et al. Among authors: van wijk xm, van gemst jj, van kuppevelt th, van der vlag j. Kidney Int. 2014 Nov;86(5):932-42. doi: 10.1038/ki.2014.115. Epub 2014 Apr 23. Kidney Int. 2014. PMID: 24759151 Free article.
Deeper penetration of erythrocytes into the endothelial glycocalyx is associated with impaired microvascular perfusion.
Lee DH, Dane MJ, van den Berg BM, Boels MG, van Teeffelen JW, de Mutsert R, den Heijer M, Rosendaal FR, van der Vlag J, van Zonneveld AJ, Vink H, Rabelink TJ; NEO study group. Lee DH, et al. Among authors: van der vlag j, van teeffelen jw, van zonneveld aj, van den berg bm. PLoS One. 2014 May 9;9(5):e96477. doi: 10.1371/journal.pone.0096477. eCollection 2014. PLoS One. 2014. PMID: 24816787 Free PMC article.
208 results