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A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation.
Stobart CC, Rostad CA, Ke Z, Dillard RS, Hampton CM, Strauss JD, Yi H, Hotard AL, Meng J, Pickles RJ, Sakamoto K, Lee S, Currier MG, Moin SM, Graham BS, Boukhvalova MS, Gilbert BE, Blanco JC, Piedra PA, Wright ER, Moore ML. Stobart CC, et al. Among authors: rostad ca. Nat Commun. 2016 Dec 21;7:13916. doi: 10.1038/ncomms13916. Nat Commun. 2016. PMID: 28000669 Free PMC article.
Evaluation of the role of respiratory syncytial virus surface glycoproteins F and G on viral stability and replication: implications for future vaccine design.
DeFord DM, Nosek JM, Castiglia KR, Hasik EF, Franke ME, Nick BC, Abdelnour AM, Haas CE, Junod NA, Latsko KN, Moore ML, Berthrong ST, Rostad CA, Stobart CC. DeFord DM, et al. Among authors: rostad ca. J Gen Virol. 2019 Jul;100(7):1112-1122. doi: 10.1099/jgv.0.001287. Epub 2019 Jun 11. J Gen Virol. 2019. PMID: 31184573
Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults.
Anderson EJ, Rouphael NG, Widge AT, Jackson LA, Roberts PC, Makhene M, Chappell JD, Denison MR, Stevens LJ, Pruijssers AJ, McDermott AB, Flach B, Lin BC, Doria-Rose NA, O'Dell S, Schmidt SD, Corbett KS, Swanson PA 2nd, Padilla M, Neuzil KM, Bennett H, Leav B, Makowski M, Albert J, Cross K, Edara VV, Floyd K, Suthar MS, Martinez DR, Baric R, Buchanan W, Luke CJ, Phadke VK, Rostad CA, Ledgerwood JE, Graham BS, Beigel JH; mRNA-1273 Study Group. Anderson EJ, et al. Among authors: rostad ca. N Engl J Med. 2020 Dec 17;383(25):2427-2438. doi: 10.1056/NEJMoa2028436. Epub 2020 Sep 29. N Engl J Med. 2020. PMID: 32991794 Free PMC article. Clinical Trial.
A Respiratory Syncytial Virus Attachment Gene Variant Associated with More Severe Disease in Infants Decreases Fusion Protein Expression, Which May Facilitate Immune Evasion.
Human S, Hotard AL, Rostad CA, Lee S, McCormick L, Larkin EK, Peret TCT, Jorba J, Lanzone J, Gebretsadik T, Williams JV, Bloodworth M, Stier M, Carroll K, Peebles RS Jr,, Anderson LJ, Hartert TV, Moore ML. Human S, et al. Among authors: rostad ca. J Virol. 2020 Dec 22;95(2):e01201-20. doi: 10.1128/JVI.01201-20. Print 2020 Dec 22. J Virol. 2020. PMID: 33115881 Free PMC article.
Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination.
Widge AT, Rouphael NG, Jackson LA, Anderson EJ, Roberts PC, Makhene M, Chappell JD, Denison MR, Stevens LJ, Pruijssers AJ, McDermott AB, Flach B, Lin BC, Doria-Rose NA, O'Dell S, Schmidt SD, Neuzil KM, Bennett H, Leav B, Makowski M, Albert J, Cross K, Edara VV, Floyd K, Suthar MS, Buchanan W, Luke CJ, Ledgerwood JE, Mascola JR, Graham BS, Beigel JH; mRNA-1273 Study Group. Widge AT, et al. N Engl J Med. 2021 Jan 7;384(1):80-82. doi: 10.1056/NEJMc2032195. Epub 2020 Dec 3. N Engl J Med. 2021. PMID: 33270381 Free PMC article. No abstract available.
93 results