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PDK1 Determines Collagen-Dependent Platelet Ca2+ Signaling and Is Critical to Development of Ischemic Stroke In Vivo.
Münzer P, Walker-Allgaier B, Geue S, Geuss E, Hron G, Rath D, Eißler D, Winter S, Schaeffeler E, Meinert M, Schaller M, Greinacher A, Schwab M, Geisler T, Kleinschnitz C, Lang F, Gawaz M, Borst O. Münzer P, et al. Among authors: geuss e. Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1507-16. doi: 10.1161/ATVBAHA.115.307105. Epub 2016 Jun 23. Arterioscler Thromb Vasc Biol. 2016. PMID: 27339458
TMEM16F-Mediated Platelet Membrane Phospholipid Scrambling Is Critical for Hemostasis and Thrombosis but not Thromboinflammation in Mice-Brief Report.
Baig AA, Haining EJ, Geuss E, Beck S, Swieringa F, Wanitchakool P, Schuhmann MK, Stegner D, Kunzelmann K, Kleinschnitz C, Heemskerk JW, Braun A, Nieswandt B. Baig AA, et al. Among authors: geuss e. Arterioscler Thromb Vasc Biol. 2016 Nov;36(11):2152-2157. doi: 10.1161/ATVBAHA.116.307727. Epub 2016 Sep 15. Arterioscler Thromb Vasc Biol. 2016. PMID: 27634832
CK2β regulates thrombopoiesis and Ca2+-triggered platelet activation in arterial thrombosis.
Münzer P, Walker-Allgaier B, Geue S, Langhauser F, Geuss E, Stegner D, Aurbach K, Semeniak D, Chatterjee M, Gonzalez Menendez I, Märklin M, Quintanilla-Martinez L, Salih HR, Litchfield DW, Buchou T, Kleinschnitz C, Lang F, Nieswandt B, Pleines I, Schulze H, Gawaz M, Borst O. Münzer P, et al. Among authors: geuss e. Blood. 2017 Dec 21;130(25):2774-2785. doi: 10.1182/blood-2017-05-784413. Epub 2017 Sep 19. Blood. 2017. PMID: 28928125 Free article.
Thromboinflammation in Stroke Brain Damage.
De Meyer SF, Denorme F, Langhauser F, Geuss E, Fluri F, Kleinschnitz C. De Meyer SF, et al. Among authors: geuss e. Stroke. 2016 Apr;47(4):1165-72. doi: 10.1161/STROKEAHA.115.011238. Epub 2016 Jan 19. Stroke. 2016. PMID: 26786115 Review. No abstract available.
NOX4 is an early initiator of neuropathic pain.
Geis C, Geuss E, Sommer C, Schmidt HH, Kleinschnitz C. Geis C, et al. Among authors: geuss e. Exp Neurol. 2017 Feb;288:94-103. doi: 10.1016/j.expneurol.2016.11.008. Epub 2016 Nov 14. Exp Neurol. 2017. PMID: 27856286
NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage.
Casas AI, Geuss E, Kleikers PWM, Mencl S, Herrmann AM, Buendia I, Egea J, Meuth SG, Lopez MG, Kleinschnitz C, Schmidt HHHW. Casas AI, et al. Among authors: geuss e. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12315-12320. doi: 10.1073/pnas.1705034114. Epub 2017 Oct 31. Proc Natl Acad Sci U S A. 2017. PMID: 29087944 Free PMC article.
PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity.
Anquetil T, Solinhac R, Jaffre A, Chicanne G, Viaud J, Darcourt J, Orset C, Geuss E, Kleinschnitz C, Vanhaesebroeck B, Vivien D, Hnia K, Larrue V, Payrastre B, Gratacap MP. Anquetil T, et al. Among authors: geuss e. EMBO Rep. 2021 Jun 4;22(6):e51299. doi: 10.15252/embr.202051299. Epub 2021 Apr 20. EMBO Rep. 2021. PMID: 33880878 Free PMC article.
A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection.
Langhauser F, Casas AI, Dao VT, Guney E, Menche J, Geuss E, Kleikers PWM, López MG, Barabási AL, Kleinschnitz C, Schmidt HHHW. Langhauser F, et al. Among authors: geuss e. NPJ Syst Biol Appl. 2018 Feb 5;4:8. doi: 10.1038/s41540-017-0039-7. eCollection 2018. NPJ Syst Biol Appl. 2018. PMID: 29423274 Free PMC article.
11 results