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Proof-of-Principle for Immune Control of Global HIV-1 Reactivation In Vivo.
Smith NM, Mlcochova P, Watters SA, Aasa-Chapman MM, Rabin N, Moore S, Edwards SG, Garson JA, Grant PR, Ferns RB, Kashuba A, Mayor NP, Schellekens J, Marsh SG, McMichael AJ, Perelson AS, Pillay D, Goonetilleke N, Gupta RK. Smith NM, et al. Among authors: goonetilleke n. Clin Infect Dis. 2015 Jul 1;61(1):120-8. doi: 10.1093/cid/civ219. Epub 2015 Mar 16. Clin Infect Dis. 2015. PMID: 25778749 Free PMC article.
Harnessing CD8+ T Cells Under HIV Antiretroviral Therapy.
Warren JA, Clutton G, Goonetilleke N. Warren JA, et al. Among authors: goonetilleke n. Front Immunol. 2019 Feb 26;10:291. doi: 10.3389/fimmu.2019.00291. eCollection 2019. Front Immunol. 2019. PMID: 30863403 Free PMC article. Review.
The HIV-1 latent reservoir is largely sensitive to circulating T cells.
Warren JA, Zhou S, Xu Y, Moeser MJ, MacMillan DR, Council O, Kirchherr J, Sung JM, Roan NR, Adimora AA, Joseph S, Kuruc JD, Gay CL, Margolis DM, Archin N, Brumme ZL, Swanstrom R, Goonetilleke N. Warren JA, et al. Among authors: goonetilleke n. Elife. 2020 Oct 6;9:e57246. doi: 10.7554/eLife.57246. Elife. 2020. PMID: 33021198 Free PMC article.
The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation.
Abrahams MR, Joseph SB, Garrett N, Tyers L, Moeser M, Archin N, Council OD, Matten D, Zhou S, Doolabh D, Anthony C, Goonetilleke N, Karim SA, Margolis DM, Pond SK, Williamson C, Swanstrom R. Abrahams MR, et al. Among authors: goonetilleke n. Sci Transl Med. 2019 Oct 9;11(513):eaaw5589. doi: 10.1126/scitranslmed.aaw5589. Sci Transl Med. 2019. PMID: 31597754 Free PMC article.
HIV-Specific, Ex Vivo Expanded T Cell Therapy: Feasibility, Safety, and Efficacy in ART-Suppressed HIV-Infected Individuals.
Sung JA, Patel S, Clohosey ML, Roesch L, Tripic T, Kuruc JD, Archin N, Hanley PJ, Cruz CR, Goonetilleke N, Eron JJ, Rooney CM, Gay CL, Bollard CM, Margolis DM. Sung JA, et al. Among authors: goonetilleke n. Mol Ther. 2018 Oct 3;26(10):2496-2506. doi: 10.1016/j.ymthe.2018.08.015. Epub 2018 Sep 21. Mol Ther. 2018. PMID: 30249388 Free PMC article. Clinical Trial.
86 results