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Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.
Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ. Egan DF, et al. Among authors: hansen m. Science. 2011 Jan 28;331(6016):456-61. doi: 10.1126/science.1196371. Epub 2010 Dec 23. Science. 2011. PMID: 21205641 Free PMC article.
Autophagy links lipid metabolism to longevity in C. elegans.
Lapierre LR, Meléndez A, Hansen M. Lapierre LR, et al. Among authors: hansen m. Autophagy. 2012 Jan;8(1):144-6. doi: 10.4161/auto.8.1.18722. Epub 2012 Jan 1. Autophagy. 2012. PMID: 22186228 Free PMC article.
Lessons from C. elegans: signaling pathways for longevity.
Lapierre LR, Hansen M. Lapierre LR, et al. Among authors: hansen m. Trends Endocrinol Metab. 2012 Dec;23(12):637-44. doi: 10.1016/j.tem.2012.07.007. Epub 2012 Aug 30. Trends Endocrinol Metab. 2012. PMID: 22939742 Free PMC article. Review.
Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans.
Schiavi A, Torgovnick A, Kell A, Megalou E, Castelein N, Guccini I, Marzocchella L, Gelino S, Hansen M, Malisan F, Condò I, Bei R, Rea SL, Braeckman BP, Tavernarakis N, Testi R, Ventura N. Schiavi A, et al. Among authors: hansen m. Exp Gerontol. 2013 Feb;48(2):191-201. doi: 10.1016/j.exger.2012.12.002. Epub 2012 Dec 13. Exp Gerontol. 2013. PMID: 23247094 Free PMC article.
Autophagy genes are required for normal lipid levels in C. elegans.
Lapierre LR, Silvestrini MJ, Nuñez L, Ames K, Wong S, Le TT, Hansen M, Meléndez A. Lapierre LR, et al. Among authors: hansen m. Autophagy. 2013 Mar;9(3):278-86. doi: 10.4161/auto.22930. Epub 2013 Jan 15. Autophagy. 2013. PMID: 23321914 Free PMC article.
Autophagy - An Emerging Anti-Aging Mechanism.
Gelino S, Hansen M. Gelino S, et al. Among authors: hansen m. J Clin Exp Pathol. 2012 Jul 12;Suppl 4:006. doi: 10.4172/2161-0681.s4-006. J Clin Exp Pathol. 2012. PMID: 23750326 Free PMC article.
5,042 results