Brough D - Search Results

1

Novel perspectives on non-canonical inflammasome activation.

Diamond CE, Khameneh HJ, Brough D, Mortellaro A. Diamond CE, et al. Among authors: brough d. Immunotargets Ther. 2015 Jul 24;4:131-41. doi: 10.2147/ITT.S57976. eCollection 2015. Immunotargets Ther. 2015. PMID: 27471719 Free PMC article. Review.

2

Inflammasome-dependent IL-1β release depends upon membrane permeabilisation.

Martín-Sánchez F, Diamond C, Zeitler M, Gomez AI, Baroja-Mazo A, Bagnall J, Spiller D, White M, Daniels MJ, Mortellaro A, Peñalver M, Paszek P, Steringer JP, Nickel W, Brough D, Pelegrín P. Martín-Sánchez F, et al. Among authors: brough d. Cell Death Differ. 2016 Jul;23(7):1219-31. doi: 10.1038/cdd.2015.176. Epub 2016 Feb 12. Cell Death Differ. 2016. PMID: 26868913 Free PMC article.

3

Investigating IL-1β Secretion Using Real-Time Single-Cell Imaging.

Diamond C, Bagnall J, Spiller DG, White MR, Mortellaro A, Paszek P, Brough D. Diamond C, et al. Among authors: brough d. Methods Mol Biol. 2016;1417:75-88. doi: 10.1007/978-1-4939-3566-6_4. Methods Mol Biol. 2016. PMID: 27221482

4

Salmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis.

Diamond CE, Leong KWK, Vacca M, Rivers-Auty J, Brough D, Mortellaro A. Diamond CE, et al. Among authors: brough d. Sci Rep. 2017 Jul 31;7(1):6861. doi: 10.1038/s41598-017-07081-3. Sci Rep. 2017. PMID: 28761045 Free PMC article.

5

Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages.

Luheshi NM, Giles JA, Lopez-Castejon G, Brough D. Luheshi NM, et al. Among authors: brough d. Eur J Immunol. 2012 Mar;42(3):716-25. doi: 10.1002/eji.201142079. Epub 2011 Dec 27. Eur J Immunol. 2012. PMID: 22105559 Free PMC article.

6

NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury.

Savage CD, Lopez-Castejon G, Denes A, Brough D. Savage CD, et al. Among authors: brough d. Front Immunol. 2012 Sep 18;3:288. doi: 10.3389/fimmu.2012.00288. eCollection 2012. Front Immunol. 2012. PMID: 23024646 Free PMC article.

7

Potassium efflux fires the canon: Potassium efflux as a common trigger for canonical and noncanonical NLRP3 pathways.

Rivers-Auty J, Brough D. Rivers-Auty J, et al. Among authors: brough d. Eur J Immunol. 2015 Oct;45(10):2758-61. doi: 10.1002/eji.201545958. Epub 2015 Sep 21. Eur J Immunol. 2015. PMID: 26332156 Free article. Review.

8

Inhibiting the Inflammasome: A Chemical Perspective.

Baldwin AG, Brough D, Freeman S. Baldwin AG, et al. Among authors: brough d. J Med Chem. 2016 Mar 10;59(5):1691-710. doi: 10.1021/acs.jmedchem.5b01091. Epub 2015 Oct 12. J Med Chem. 2016. PMID: 26422006 Review.

9

Is Targeting the Inflammasome a Way Forward for Neuroscience Drug Discovery?

Swanton T, Cook J, Beswick JA, Freeman S, Lawrence CB, Brough D. Swanton T, et al. Among authors: brough d. SLAS Discov. 2018 Dec;23(10):991-1017. doi: 10.1177/2472555218786210. Epub 2018 Jul 3. SLAS Discov. 2018. PMID: 29969573 Free article. Review.

10

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation.

Palazón-Riquelme P, Worboys JD, Green J, Valera A, Martín-Sánchez F, Pellegrini C, Brough D, López-Castejón G. Palazón-Riquelme P, et al. Among authors: brough d. EMBO Rep. 2018 Oct;19(10):e44766. doi: 10.15252/embr.201744766. Epub 2018 Sep 11. EMBO Rep. 2018. PMID: 30206189 Free PMC article.

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