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Plasma inflammatory and apoptosis markers are associated with dialysis dependence and death among critically ill patients receiving renal replacement therapy.
Murugan R, Wen X, Shah N, Lee M, Kong L, Pike F, Keener C, Unruh M, Finkel K, Vijayan A, Palevsky PM, Paganini E, Carter M, Elder M, Kellum JA; Biological Markers for Recovery of Kidney (BioMaRK) Study Investigators. Murugan R, et al. Nephrol Dial Transplant. 2014 Oct;29(10):1854-64. doi: 10.1093/ndt/gfu051. Epub 2014 Mar 11. Nephrol Dial Transplant. 2014. PMID: 24619058 Free PMC article.
A randomized trial of protocol-based care for early septic shock.
ProCESS Investigators; Yealy DM, Kellum JA, Huang DT, Barnato AE, Weissfeld LA, Pike F, Terndrup T, Wang HE, Hou PC, LoVecchio F, Filbin MR, Shapiro NI, Angus DC. ProCESS Investigators, et al. N Engl J Med. 2014 May 1;370(18):1683-93. doi: 10.1056/NEJMoa1401602. Epub 2014 Mar 18. N Engl J Med. 2014. PMID: 24635773 Free PMC article. Clinical Trial.
Associations between Intensity of RRT, Inflammatory Mediators, and Outcomes.
Murugan R, Wen X, Keener C, Pike F, Palevsky PM, Unruh M, Finkel K, Vijayan A, Elder M, Chen YF, Kellum JA; Biological Markers of Recovery for the Kidney (BioMaRK) Study Investigators. Murugan R, et al. Clin J Am Soc Nephrol. 2015 Jun 5;10(6):926-33. doi: 10.2215/CJN.04560514. Epub 2015 Apr 10. Clin J Am Soc Nephrol. 2015. PMID: 25862777 Free PMC article. Clinical Trial.
Sepsis-Associated Acute Kidney Disease.
Peerapornratana S, Priyanka P, Wang S, Smith A, Singbartl K, Palevsky PM, Chawla LS, Yealy DM, Angus DC, Kellum JA; ProCESS and ProGReSS-AKI Investigators. Peerapornratana S, et al. Kidney Int Rep. 2020 Mar 12;5(6):839-850. doi: 10.1016/j.ekir.2020.03.005. eCollection 2020 Jun. Kidney Int Rep. 2020. PMID: 32518866 Free PMC article.
Serial Measurement of Cell-Cycle Arrest Biomarkers [TIMP-2] · [IGFBP7] and Risk for Progression to Death, Dialysis, or Severe Acute Kidney Injury in Patients with Septic Shock.
Fiorentino M, Xu Z, Smith A, Singbartl K, Palevsky PM, Chawla LS, Huang DT, Yealy DM, Angus DC, Kellum JA; ProCESS and ProGReSS-AKI Investigators. Fiorentino M, et al. Am J Respir Crit Care Med. 2020 Nov 1;202(9):1262-1270. doi: 10.1164/rccm.201906-1197OC. Am J Respir Crit Care Med. 2020. PMID: 32584598 Free PMC article.
Limiting Acute Kidney Injury Progression In Sepsis: Study Protocol and Trial Simulation.
Molinari L, Heskia F, Peerapornratana S, Ronco C, Guzzi L, Toback S, Birch R, Beyhaghi H, Kwan T, Kampf JP, Yealy DM, Kellum JA; Sapphire and Protocolized Care for Early Septic Shock (ProCESS) Investigators. Molinari L, et al. Crit Care Med. 2021 Oct 1;49(10):1706-1716. doi: 10.1097/CCM.0000000000005061. Crit Care Med. 2021. PMID: 33927121 Free PMC article.
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