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CD8+ T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold.
Dockree T, Holland CJ, Clement M, Ladell K, McLaren JE, van den Berg HA, Gostick E, L Miners K, Llewellyn-Lacey S, Bridgeman JS, Man S, Bailey M, Burrows SR, Price DA, Wooldridge L. Dockree T, et al. Among authors: van den berg ha. Immunol Cell Biol. 2017 Jan;95(1):68-76. doi: 10.1038/icb.2016.85. Epub 2016 Nov 8. Immunol Cell Biol. 2017. PMID: 27670790 Free PMC article.
Dynamics of T cell activation threshold tuning.
van den Berg HA, Rand DA. van den Berg HA, et al. J Theor Biol. 2004 Jun 7;228(3):397-416. doi: 10.1016/j.jtbi.2004.02.002. J Theor Biol. 2004. PMID: 15135038
Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface.
Wooldridge L, van den Berg HA, Glick M, Gostick E, Laugel B, Hutchinson SL, Milicic A, Brenchley JM, Douek DC, Price DA, Sewell AK. Wooldridge L, et al. Among authors: van den berg ha. J Biol Chem. 2005 Jul 29;280(30):27491-501. doi: 10.1074/jbc.M500555200. Epub 2005 Apr 18. J Biol Chem. 2005. PMID: 15837791 Free PMC article.
Detection of low avidity CD8(+) T cell populations with coreceptor-enhanced peptide-major histocompatibility complex class I tetramers.
Melenhorst JJ, Scheinberg P, Chattopadhyay PK, Lissina A, Gostick E, Cole DK, Wooldridge L, van den Berg HA, Bornstein E, Hensel NF, Douek DC, Roederer M, Sewell AK, Barrett AJ, Price DA. Melenhorst JJ, et al. Among authors: van den berg ha. J Immunol Methods. 2008 Sep 30;338(1-2):31-9. doi: 10.1016/j.jim.2008.07.008. Epub 2008 Jul 31. J Immunol Methods. 2008. PMID: 18675271 Free PMC article.
Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers.
Lissina A, Ladell K, Skowera A, Clement M, Edwards E, Seggewiss R, van den Berg HA, Gostick E, Gallagher K, Jones E, Melenhorst JJ, Godkin AJ, Peakman M, Price DA, Sewell AK, Wooldridge L. Lissina A, et al. Among authors: van den berg ha. J Immunol Methods. 2009 Jan 1;340(1):11-24. doi: 10.1016/j.jim.2008.09.014. Epub 2008 Oct 16. J Immunol Methods. 2009. PMID: 18929568 Free PMC article.
Tricks with tetramers: how to get the most from multimeric peptide-MHC.
Wooldridge L, Lissina A, Cole DK, van den Berg HA, Price DA, Sewell AK. Wooldridge L, et al. Among authors: van den berg ha. Immunology. 2009 Feb;126(2):147-64. doi: 10.1111/j.1365-2567.2008.02848.x. Immunology. 2009. PMID: 19125886 Free PMC article. Review.
109 results