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Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late INai), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties.
J Med Chem. 2016 Oct 13;59(19):9005-9017. doi: 10.1021/acs.jmedchem.6b00939. Epub 2016 Oct 3.
J Med Chem. 2016.
PMID: 27690427
Structure-guided design of peptide-based tryptase inhibitors.
McGrath ME, Sprengeler PA, Hirschbein B, Somoza JR, Lehoux I, Janc JW, Gjerstad E, Graupe M, Estiarte A, Venkataramani C, Liu Y, Yee R, Ho JD, Green MJ, Lee CS, Liu L, Tai V, Spencer J, Sperandio D, Katz BA.
McGrath ME, et al. Among authors: venkataramani c.
Biochemistry. 2006 May 16;45(19):5964-73. doi: 10.1021/bi060173m.
Biochemistry. 2006.
PMID: 16681368
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Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids.
Jenkins RW, Aref AR, Lizotte PH, Ivanova E, Stinson S, Zhou CW, Bowden M, Deng J, Liu H, Miao D, He MX, Walker W, Zhang G, Tian T, Cheng C, Wei Z, Palakurthi S, Bittinger M, Vitzthum H, Kim JW, Merlino A, Quinn M, Venkataramani C, Kaplan JA, Portell A, Gokhale PC, Phillips B, Smart A, Rotem A, Jones RE, Keogh L, Anguiano M, Stapleton L, Jia Z, Barzily-Rokni M, Cañadas I, Thai TC, Hammond MR, Vlahos R, Wang ES, Zhang H, Li S, Hanna GJ, Huang W, Hoang MP, Piris A, Eliane JP, Stemmer-Rachamimov AO, Cameron L, Su MJ, Shah P, Izar B, Thakuria M, LeBoeuf NR, Rabinowits G, Gunda V, Parangi S, Cleary JM, Miller BC, Kitajima S, Thummalapalli R, Miao B, Barbie TU, Sivathanu V, Wong J, Richards WG, Bueno R, Yoon CH, Miret J, Herlyn M, Garraway LA, Van Allen EM, Freeman GJ, Kirschmeier PT, Lorch JH, Ott PA, Hodi FS, Flaherty KT, Kamm RD, Boland GM, Wong KK, Dornan D, Paweletz CP, Barbie DA.
Jenkins RW, et al. Among authors: venkataramani c.
Cancer Discov. 2018 Feb;8(2):196-215. doi: 10.1158/2159-8290.CD-17-0833. Epub 2017 Nov 3.
Cancer Discov. 2018.
PMID: 29101162
Free PMC article.
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Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency.
Farand J, Mai N, Chandrasekhar J, Newby ZE, Van Veldhuizen J, Loyer-Drew J, Venkataramani C, Guerrero J, Kwok A, Li N, Zherebina Y, Wilbert S, Zablocki J, Phillips G, Watkins WJ, Mourey R, Notte GT.
Farand J, et al. Among authors: venkataramani c.
Bioorg Med Chem Lett. 2016 Dec 15;26(24):5926-5930. doi: 10.1016/j.bmcl.2016.10.092. Epub 2016 Nov 2.
Bioorg Med Chem Lett. 2016.
PMID: 27876318
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New strategic reactions for organic synthesis: catalytic asymmetric C-H activation alpha to nitrogen as a surrogate for the mannich reaction.
Davies HM, Venkataramani C, Hansen T, Hopper DW.
Davies HM, et al. Among authors: venkataramani c.
J Am Chem Soc. 2003 May 28;125(21):6462-8. doi: 10.1021/ja0290072.
J Am Chem Soc. 2003.
PMID: 12785786
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Dirhodium tetraprolinate-catalyzed asymmetric cyclopropanations with high turnover numbers.
Davies HM, Venkataramani C.
Davies HM, et al. Among authors: venkataramani c.
Org Lett. 2003 May 1;5(9):1403-6. doi: 10.1021/ol034002a.
Org Lett. 2003.
PMID: 12713284
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Catalytic enantioselective synthesis of beta3-amino acids.
Davies HM, Venkataramani C.
Davies HM, et al. Among authors: venkataramani c.
Angew Chem Int Ed Engl. 2002 Jun 17;41(12):2197-9.
Angew Chem Int Ed Engl. 2002.
PMID: 19746643
No abstract available.
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Kinetic resolution and double stereodifferentiation in catalytic asymmetric C-H activation of 2-substituted pyrrolidines.
Davies HM, Venkataramani C.
Davies HM, et al. Among authors: venkataramani c.
Org Lett. 2001 May 31;3(11):1773-5. doi: 10.1021/ol015974q.
Org Lett. 2001.
PMID: 11405708
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