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Anti-Hinge Antibodies Recognize IgG Subclass- and Protease-Restricted Neoepitopes.
Falkenburg WJ, van Schaardenburg D, Ooijevaar-de Heer P, Tsang-A-Sjoe MW, Bultink IE, Voskuyl AE, Bentlage AE, Vidarsson G, Wolbink G, Rispens T. Falkenburg WJ, et al. Among authors: rispens t. J Immunol. 2017 Jan 1;198(1):82-93. doi: 10.4049/jimmunol.1601096. Epub 2016 Nov 18. J Immunol. 2017. PMID: 27864476
Mechanism of immunoglobulin G4 Fab-arm exchange.
Rispens T, Ooijevaar-de Heer P, Bende O, Aalberse RC. Rispens T, et al. J Am Chem Soc. 2011 Jul 6;133(26):10302-11. doi: 10.1021/ja203638y. Epub 2011 Jun 15. J Am Chem Soc. 2011. PMID: 21627172
Species-specific determinants in the IgG CH3 domain enable Fab-arm exchange by affecting the noncovalent CH3-CH3 interaction strength.
Labrijn AF, Rispens T, Meesters J, Rose RJ, den Bleker TH, Loverix S, van den Bremer ET, Neijssen J, Vink T, Lasters I, Aalberse RC, Heck AJ, van de Winkel JG, Schuurman J, Parren PW. Labrijn AF, et al. Among authors: rispens t. J Immunol. 2011 Sep 15;187(6):3238-46. doi: 10.4049/jimmunol.1003336. Epub 2011 Aug 12. J Immunol. 2011. PMID: 21841137
IgG4 production against adalimumab during long term treatment of RA patients.
van Schouwenburg PA, Krieckaert CL, Nurmohamed M, Hart M, Rispens T, Aarden L, Wouters D, Wolbink GJ. van Schouwenburg PA, et al. Among authors: rispens t. J Clin Immunol. 2012 Oct;32(5):1000-6. doi: 10.1007/s10875-012-9705-0. Epub 2012 May 24. J Clin Immunol. 2012. PMID: 22622790
Adalimumab elicits a restricted anti-idiotypic antibody response in autoimmune patients resulting in functional neutralisation.
van Schouwenburg PA, van de Stadt LA, de Jong RN, van Buren EE, Kruithof S, de Groot E, Hart M, van Ham SM, Rispens T, Aarden L, Wolbink GJ, Wouters D. van Schouwenburg PA, et al. Among authors: rispens t. Ann Rheum Dis. 2013 Jan;72(1):104-9. doi: 10.1136/annrheumdis-2012-201445. Epub 2012 Jul 3. Ann Rheum Dis. 2013. PMID: 22759910
291 results