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Hepatocellular carcinoma cells and their fibrotic microenvironment modulate bone marrow-derived mesenchymal stromal cell migration in vitro and in vivo.
Garcia MG, Bayo J, Bolontrade MF, Sganga L, Malvicini M, Alaniz L, Aquino JB, Fiore E, Rizzo MM, Rodriguez A, Lorenti A, Andriani O, Podhajcer O, Mazzolini G. Garcia MG, et al. Among authors: fiore e. Mol Pharm. 2011 Oct 3;8(5):1538-48. doi: 10.1021/mp200137c. Epub 2011 Aug 19. Mol Pharm. 2011. PMID: 21770423
Lack of the matricellular protein SPARC (secreted protein, acidic and rich in cysteine) attenuates liver fibrogenesis in mice.
Atorrasagasti C, Peixoto E, Aquino JB, Kippes N, Malvicini M, Alaniz L, Garcia M, Piccioni F, Fiore EJ, Bayo J, Bataller R, Guruceaga E, Corrales F, Podhajcer O, Mazzolini G. Atorrasagasti C, et al. Among authors: fiore ej. PLoS One. 2013;8(2):e54962. doi: 10.1371/journal.pone.0054962. Epub 2013 Feb 11. PLoS One. 2013. PMID: 23408952 Free PMC article.
Increased migration of human mesenchymal stromal cells by autocrine motility factor (AMF) resulted in enhanced recruitment towards hepatocellular carcinoma.
Bayo J, Fiore E, Aquino JB, Malvicini M, Rizzo M, Peixoto E, Andriani O, Alaniz L, Piccioni F, Bolontrade M, Podhajcer O, Garcia MG, Mazzolini G. Bayo J, et al. Among authors: fiore e. PLoS One. 2014 Apr 15;9(4):e95171. doi: 10.1371/journal.pone.0095171. eCollection 2014. PLoS One. 2014. PMID: 24736611 Free PMC article.
Human umbilical cord perivascular cells exhibited enhanced migration capacity towards hepatocellular carcinoma in comparison with bone marrow mesenchymal stromal cells: a role for autocrine motility factor receptor.
Bayo J, Fiore E, Aquino JB, Malvicini M, Rizzo M, Peixoto E, Alaniz L, Piccioni F, Bolontrade M, Podhajcer O, Garcia MG, Mazzolini G. Bayo J, et al. Among authors: fiore e. Biomed Res Int. 2014;2014:837420. doi: 10.1155/2014/837420. Epub 2014 Jul 23. Biomed Res Int. 2014. PMID: 25147818 Free PMC article.
Low molecular weight hyaluronan-pulsed human dendritic cells showed increased migration capacity and induced resistance to tumor chemoattraction.
Rizzo M, Bayo J, Piccioni F, Malvicini M, Fiore E, Peixoto E, García MG, Aquino JB, Gonzalez Campaña A, Podestá G, Terres M, Andriani O, Alaniz L, Mazzolini G. Rizzo M, et al. Among authors: fiore e. PLoS One. 2014 Sep 19;9(9):e107944. doi: 10.1371/journal.pone.0107944. eCollection 2014. PLoS One. 2014. PMID: 25238610 Free PMC article.
SPARC (secreted protein acidic and rich in cysteine) knockdown protects mice from acute liver injury by reducing vascular endothelial cell damage.
Peixoto E, Atorrasagasti C, Aquino JB, Militello R, Bayo J, Fiore E, Piccioni F, Salvatierra E, Alaniz L, García MG, Bataller R, Corrales F, Gidekel M, Podhajcer O, Colombo MI, Mazzolini G. Peixoto E, et al. Among authors: fiore e. Gene Ther. 2015 Jan;22(1):9-19. doi: 10.1038/gt.2014.102. Epub 2014 Nov 20. Gene Ther. 2015. PMID: 25410742 Free PMC article.
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