D'Andrea AD - Search Results

1

CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer.

Johnson SF, Cruz C, Greifenberg AK, Dust S, Stover DG, Chi D, Primack B, Cao S, Bernhardy AJ, Coulson R, Lazaro JB, Kochupurakkal B, Sun H, Unitt C, Moreau LA, Sarosiek KA, Scaltriti M, Juric D, Baselga J, Richardson AL, Rodig SJ, D'Andrea AD, Balmaña J, Johnson N, Geyer M, Serra V, Lim E, Shapiro GI. Johnson SF, et al. Cell Rep. 2016 Nov 22;17(9):2367-2381. doi: 10.1016/j.celrep.2016.10.077. Cell Rep. 2016. PMID: 27880910 Free PMC article.

2

A novel diagnostic screen for defects in the Fanconi anemia pathway.

Shimamura A, Montes de Oca R, Svenson JL, Haining N, Moreau LA, Nathan DG, D'Andrea AD. Shimamura A, et al. Blood. 2002 Dec 15;100(13):4649-54. doi: 10.1182/blood-2002-05-1399. Epub 2002 Aug 29. Blood. 2002. PMID: 12393398 Free article.

3

Interaction of FANCD2 and NBS1 in the DNA damage response.

Nakanishi K, Taniguchi T, Ranganathan V, New HV, Moreau LA, Stotsky M, Mathew CG, Kastan MB, Weaver DT, D'Andrea AD. Nakanishi K, et al. Nat Cell Biol. 2002 Dec;4(12):913-20. doi: 10.1038/ncb879. Nat Cell Biol. 2002. PMID: 12447395

4

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.

Smogorzewska A, Matsuoka S, Vinciguerra P, McDonald ER 3rd, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K, D'Andrea AD, Elledge SJ. Smogorzewska A, et al. Cell. 2007 Apr 20;129(2):289-301. doi: 10.1016/j.cell.2007.03.009. Epub 2007 Apr 5. Cell. 2007. PMID: 17412408 Free PMC article.

5

Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated.

Kennedy RD, Chen CC, Stuckert P, Archila EM, De la Vega MA, Moreau LA, Shimamura A, D'Andrea AD. Kennedy RD, et al. J Clin Invest. 2007 May;117(5):1440-9. doi: 10.1172/JCI31245. Epub 2007 Apr 12. J Clin Invest. 2007. PMID: 17431503 Free PMC article.

6

Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage.

Johnson N, Cai D, Kennedy RD, Pathania S, Arora M, Li YC, D'Andrea AD, Parvin JD, Shapiro GI. Johnson N, et al. Mol Cell. 2009 Aug 14;35(3):327-39. doi: 10.1016/j.molcel.2009.06.036. Mol Cell. 2009. PMID: 19683496 Free PMC article.

7

FANCD2 hurdles the DNA interstrand crosslink.

Moldovan GL, D'Andrea AD. Moldovan GL, et al. Cell. 2009 Dec 24;139(7):1222-4. doi: 10.1016/j.cell.2009.12.006. Cell. 2009. PMID: 20064367 Free PMC article.

8

Targeting DNA repair pathways in AML.

D'Andrea AD. D'Andrea AD. Best Pract Res Clin Haematol. 2010 Dec;23(4):469-73. doi: 10.1016/j.beha.2010.09.005. Epub 2010 Oct 29. Best Pract Res Clin Haematol. 2010. PMID: 21130409 Review.

9

Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition.

Johnson N, Li YC, Walton ZE, Cheng KA, Li D, Rodig SJ, Moreau LA, Unitt C, Bronson RT, Thomas HD, Newell DR, D'Andrea AD, Curtin NJ, Wong KK, Shapiro GI. Johnson N, et al. Nat Med. 2011 Jun 26;17(7):875-82. doi: 10.1038/nm.2377. Nat Med. 2011. PMID: 21706030 Free PMC article.

10

Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway.

Huang M, Kennedy R, Ali AM, Moreau LA, Meetei AR, D'Andrea AD, Chen CC. Huang M, et al. DNA Repair (Amst). 2011 Dec 10;10(12):1203-12. doi: 10.1016/j.dnarep.2011.09.006. Epub 2011 Oct 4. DNA Repair (Amst). 2011. PMID: 21975120

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