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Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1.
Lee HW, Khan SQ, Khaliqdina S, Altintas MM, Grahammer F, Zhao JL, Koh KH, Tardi NJ, Faridi MH, Geraghty T, Cimbaluk DJ, Susztak K, Moita LF, Baltimore D, Tharaux PL, Huber TB, Kretzler M, Bitzer M, Reiser J, Gupta V. Lee HW, et al. Among authors: huber tb. J Biol Chem. 2017 Jan 13;292(2):732-747. doi: 10.1074/jbc.M116.753822. Epub 2016 Dec 2. J Biol Chem. 2017. PMID: 27913625 Free PMC article.
Interaction with podocin facilitates nephrin signaling.
Huber TB, Kottgen M, Schilling B, Walz G, Benzing T. Huber TB, et al. J Biol Chem. 2001 Nov 9;276(45):41543-6. doi: 10.1074/jbc.C100452200. Epub 2001 Sep 18. J Biol Chem. 2001. PMID: 11562357 Free article.
Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity.
Hartleben B, Schweizer H, Lübben P, Bartram MP, Möller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB. Hartleben B, et al. Among authors: huber tb. J Biol Chem. 2008 Aug 22;283(34):23033-8. doi: 10.1074/jbc.M803143200. Epub 2008 Jun 18. J Biol Chem. 2008. PMID: 18562307 Free PMC article.
Flying podocytes.
Simons M, Huber TB. Simons M, et al. Among authors: huber tb. Kidney Int. 2009 Mar;75(5):455-7. doi: 10.1038/ki.2008.653. Kidney Int. 2009. PMID: 19219000 Free article.
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice.
Hartleben B, Gödel M, Meyer-Schwesinger C, Liu S, Ulrich T, Köbler S, Wiech T, Grahammer F, Arnold SJ, Lindenmeyer MT, Cohen CD, Pavenstädt H, Kerjaschki D, Mizushima N, Shaw AS, Walz G, Huber TB. Hartleben B, et al. Among authors: huber tb. J Clin Invest. 2010 Apr;120(4):1084-96. doi: 10.1172/JCI39492. J Clin Invest. 2010. PMID: 20200449 Free PMC article.
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.
Gödel M, Hartleben B, Herbach N, Liu S, Zschiedrich S, Lu S, Debreczeni-Mór A, Lindenmeyer MT, Rastaldi MP, Hartleben G, Wiech T, Fornoni A, Nelson RG, Kretzler M, Wanke R, Pavenstädt H, Kerjaschki D, Cohen CD, Hall MN, Rüegg MA, Inoki K, Walz G, Huber TB. Gödel M, et al. Among authors: huber tb. J Clin Invest. 2011 Jun;121(6):2197-209. doi: 10.1172/JCI44774. Epub 2011 May 23. J Clin Invest. 2011. PMID: 21606591 Free PMC article.
mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.
Inoki K, Mori H, Wang J, Suzuki T, Hong S, Yoshida S, Blattner SM, Ikenoue T, Rüegg MA, Hall MN, Kwiatkowski DJ, Rastaldi MP, Huber TB, Kretzler M, Holzman LB, Wiggins RC, Guan KL. Inoki K, et al. Among authors: huber tb. J Clin Invest. 2011 Jun;121(6):2181-96. doi: 10.1172/JCI44771. Epub 2011 May 23. J Clin Invest. 2011. PMID: 21606597 Free PMC article.
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival.
Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, Reinheckel T, Gu C, Huber TB, Ju W, Bitzer M, Rastaldi MP, Ruiz P, Tryggvason K, Shaw AS, Faul C, Sever S, Reiser J. Yaddanapudi S, et al. Among authors: huber tb. J Clin Invest. 2011 Oct;121(10):3965-80. doi: 10.1172/JCI58552. Epub 2011 Sep 12. J Clin Invest. 2011. PMID: 21911934 Free PMC article.
Old friends form alliance against podocytes.
Simons M, Huber TB. Simons M, et al. Among authors: huber tb. Kidney Int. 2011 Dec;80(11):1117-9. doi: 10.1038/ki.2011.298. Kidney Int. 2011. PMID: 22083635 Free article.
312 results