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ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A.
Williamson CT, Miller R, Pemberton HN, Jones SE, Campbell J, Konde A, Badham N, Rafiq R, Brough R, Gulati A, Ryan CJ, Francis J, Vermulen PB, Reynolds AR, Reaper PM, Pollard JR, Ashworth A, Lord CJ. Williamson CT, et al. Among authors: reynolds ar. Nat Commun. 2016 Dec 13;7:13837. doi: 10.1038/ncomms13837. Nat Commun. 2016. PMID: 27958275 Free PMC article.
Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases.
Frentzas S, Simoneau E, Bridgeman VL, Vermeulen PB, Foo S, Kostaras E, Nathan M, Wotherspoon A, Gao ZH, Shi Y, Van den Eynden G, Daley F, Peckitt C, Tan X, Salman A, Lazaris A, Gazinska P, Berg TJ, Eltahir Z, Ritsma L, Van Rheenen J, Khashper A, Brown G, Nystrom H, Sund M, Van Laere S, Loyer E, Dirix L, Cunningham D, Metrakos P, Reynolds AR. Frentzas S, et al. Among authors: reynolds ar. Nat Med. 2016 Nov;22(11):1294-1302. doi: 10.1038/nm.4197. Epub 2016 Oct 17. Nat Med. 2016. PMID: 27748747 Free PMC article.
Non-angiogenic tumours and their influence on cancer biology.
Donnem T, Reynolds AR, Kuczynski EA, Gatter K, Vermeulen PB, Kerbel RS, Harris AL, Pezzella F. Donnem T, et al. Among authors: reynolds ar. Nat Rev Cancer. 2018 May;18(5):323-336. doi: 10.1038/nrc.2018.14. Epub 2018 Mar 9. Nat Rev Cancer. 2018. PMID: 29520090 Review.
Preclinical Evidence That Trametinib Enhances the Response to Antiangiogenic Tyrosine Kinase Inhibitors in Renal Cell Carcinoma.
Bridgeman VL, Wan E, Foo S, Nathan MR, Welti JC, Frentzas S, Vermeulen PB, Preece N, Springer CJ, Powles T, Nathan PD, Larkin J, Gore M, Vasudev NS, Reynolds AR. Bridgeman VL, et al. Among authors: reynolds ar. Mol Cancer Ther. 2016 Jan;15(1):172-83. doi: 10.1158/1535-7163.MCT-15-0170. Epub 2015 Oct 20. Mol Cancer Ther. 2016. PMID: 26487278 Free article.
Contrasting effects of sunitinib within in vivo models of metastasis.
Welti JC, Powles T, Foo S, Gourlaouen M, Preece N, Foster J, Frentzas S, Bird D, Sharpe K, van Weverwijk A, Robertson D, Soffe J, Erler JT, Pili R, Springer CJ, Mather SJ, Reynolds AR. Welti JC, et al. Among authors: reynolds ar. Angiogenesis. 2012 Dec;15(4):623-41. doi: 10.1007/s10456-012-9291-z. Epub 2012 Jul 28. Angiogenesis. 2012. PMID: 22843200 Free PMC article.
Vessel co-option in cancer.
Kuczynski EA, Vermeulen PB, Pezzella F, Kerbel RS, Reynolds AR. Kuczynski EA, et al. Among authors: reynolds ar. Nat Rev Clin Oncol. 2019 Aug;16(8):469-493. doi: 10.1038/s41571-019-0181-9. Nat Rev Clin Oncol. 2019. PMID: 30816337 Review.
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