He Y - Search Results

1

Osimertinib or Platinum-Pemetrexed in EGFR T790M-Positive Lung Cancer.

Mok TS, Wu Y-L, Ahn M-J, Garassino MC, Kim HR, Ramalingam SS, Shepherd FA, He Y, Akamatsu H, Theelen WS, Lee CK, Sebastian M, Templeton A, Mann H, Marotti M, Ghiorghiu S, Papadimitrakopoulou VA; AURA3 Investigators. Mok TS, et al. Among authors: he y. N Engl J Med. 2017 Feb 16;376(7):629-640. doi: 10.1056/NEJMoa1612674. Epub 2016 Dec 6. N Engl J Med. 2017. PMID: 27959700 Free PMC article. Clinical Trial.

2

Metformin sensitizes EGFR-TKI-resistant human lung cancer cells in vitro and in vivo through inhibition of IL-6 signaling and EMT reversal.

Li L, Han R, Xiao H, Lin C, Wang Y, Liu H, Li K, Chen H, Sun F, Yang Z, Jiang J, He Y. Li L, et al. Among authors: he y. Clin Cancer Res. 2014 May 15;20(10):2714-26. doi: 10.1158/1078-0432.CCR-13-2613. Epub 2014 Mar 18. Clin Cancer Res. 2014. PMID: 24644001

3

Extraordinary response to crizotinib in a woman with squamous cell lung cancer after two courses of failed chemotherapy.

Wang Q, He Y, Yang X, Wang Y, Xiao H. Wang Q, et al. Among authors: he y. BMC Pulm Med. 2014 May 15;14:83. doi: 10.1186/1471-2466-14-83. BMC Pulm Med. 2014. PMID: 24885608 Free PMC article.

4

A Multicenter Double-blind Phase II Study of Metformin With Gefitinib as First-line Therapy of Locally Advanced Non-Small-cell Lung Cancer.

Li KL, Li L, Zhang P, Kang J, Wang YB, Chen HY, He Y. Li KL, et al. Among authors: he y. Clin Lung Cancer. 2017 May;18(3):340-343. doi: 10.1016/j.cllc.2016.12.003. Epub 2016 Dec 22. Clin Lung Cancer. 2017. PMID: 28065465 Free article. Clinical Trial.

5

Clinical analysis by next-generation sequencing for NSCLC patients with MET amplification resistant to osimertinib.

Wang Y, Li L, Han R, Jiao L, Zheng J, He Y. Wang Y, et al. Among authors: he y. Lung Cancer. 2018 Apr;118:105-110. doi: 10.1016/j.lungcan.2018.02.007. Epub 2018 Feb 13. Lung Cancer. 2018. PMID: 29571987 Free article.

6

Metformin synergistically enhances the antitumor activity of the third-generation EGFR-TKI CO-1686 in lung cancer cells through suppressing NF-κB signaling.

Pan YH, Lin CY, Lu CH, Li L, Wang YB, Chen HY, He Y. Pan YH, et al. Among authors: he y. Clin Respir J. 2018 Dec;12(12):2642-2652. doi: 10.1111/crj.12970. Epub 2018 Nov 9. Clin Respir J. 2018. PMID: 30307719

7

Protective autophagy decreases osimertinib cytotoxicity through regulation of stem cell-like properties in lung cancer.

Li L, Wang Y, Jiao L, Lin C, Lu C, Zhang K, Hu C, Ye J, Zhang D, Wu H, Feng M, He Y. Li L, et al. Among authors: he y. Cancer Lett. 2019 Jun 28;452:191-202. doi: 10.1016/j.canlet.2019.03.027. Epub 2019 Mar 22. Cancer Lett. 2019. PMID: 30910592

8

Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial.

Mok TSK, Wu YL, Kudaba I, Kowalski DM, Cho BC, Turna HZ, Castro G Jr, Srimuninnimit V, Laktionov KK, Bondarenko I, Kubota K, Lubiniecki GM, Zhang J, Kush D, Lopes G; KEYNOTE-042 Investigators. Mok TSK, et al. Lancet. 2019 May 4;393(10183):1819-1830. doi: 10.1016/S0140-6736(18)32409-7. Epub 2019 Apr 4. Lancet. 2019. PMID: 30955977 Clinical Trial.

9

Metformin-sensitized NSCLC cells to osimertinib via AMPK-dependent autophagy inhibition.

Chen H, Lin C, Lu C, Wang Y, Han R, Li L, Hao S, He Y. Chen H, et al. Among authors: he y. Clin Respir J. 2019 Dec;13(12):781-790. doi: 10.1111/crj.13091. Epub 2019 Oct 7. Clin Respir J. 2019. PMID: 31562701

10

Serial ultra-deep sequencing of circulating tumor DNA reveals the clonal evolution in non-small cell lung cancer patients treated with anti-PD1 immunotherapy.

Li L, Wang Y, Shi W, Zhu M, Liu Z, Luo N, Zeng Y, He Y. Li L, et al. Among authors: he y. Cancer Med. 2019 Dec;8(18):7669-7678. doi: 10.1002/cam4.2632. Epub 2019 Nov 6. Cancer Med. 2019. PMID: 31692284 Free PMC article.

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