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Digital PCR dynamic range is approaching that of real-time quantitative PCR.
Jones GM, Busby E, Garson JA, Grant PR, Nastouli E, Devonshire AS, Whale AS. Jones GM, et al. Among authors: whale as. Biomol Detect Quantif. 2016 Nov 2;10:31-33. doi: 10.1016/j.bdq.2016.10.001. eCollection 2016 Dec. Biomol Detect Quantif. 2016. PMID: 27990347 Free PMC article.
An international comparability study on quantification of mRNA gene expression ratios: CCQM-P103.1.
Devonshire AS, Sanders R, Whale AS, Nixon GJ, Cowen S, Ellison SL, Parkes H, Pine PS, Salit M, McDaniel J, Munro S, Lund S, Matsukura S, Sekiguchi Y, Kawaharasaki M, Granjeiro JM, Falagan-Lotsch P, Saraiva AM, Couto P, Yang I, Kwon H, Park SR, Demšar T, Žel J, Blejec A, Milavec M, Dong L, Zhang L, Sui Z, Wang J, Viroonudomphol D, Prawettongsopon C, Partis L, Baoutina A, Emslie K, Takatsu A, Akyurek S, Akgoz M, Vonsky M, Konopelko LA, Cundapi EM, Urquiza MP, Huggett JF, Foy CA. Devonshire AS, et al. Among authors: whale as. Biomol Detect Quantif. 2016 Jun 6;8:15-28. doi: 10.1016/j.bdq.2016.05.003. eCollection 2016 Jun. Biomol Detect Quantif. 2016. PMID: 27335807 Free PMC article.
International Interlaboratory Digital PCR Study Demonstrating High Reproducibility for the Measurement of a Rare Sequence Variant.
Whale AS, Devonshire AS, Karlin-Neumann G, Regan J, Javier L, Cowen S, Fernandez-Gonzalez A, Jones GM, Redshaw N, Beck J, Berger AW, Combaret V, Dahl Kjersgaard N, Davis L, Fina F, Forshew T, Fredslund Andersen R, Galbiati S, González Hernández Á, Haynes CA, Janku F, Lacave R, Lee J, Mistry V, Pender A, Pradines A, Proudhon C, Saal LH, Stieglitz E, Ulrich B, Foy CA, Parkes H, Tzonev S, Huggett JF. Whale AS, et al. Anal Chem. 2017 Feb 7;89(3):1724-1733. doi: 10.1021/acs.analchem.6b03980. Epub 2017 Jan 18. Anal Chem. 2017. PMID: 27935690
Assessment of Digital PCR as a Primary Reference Measurement Procedure to Support Advances in Precision Medicine.
Whale AS, Jones GM, Pavšič J, Dreo T, Redshaw N, Akyürek S, Akgöz M, Divieto C, Sassi MP, He HJ, Cole KD, Bae YK, Park SR, Deprez L, Corbisier P, Garrigou S, Taly V, Larios R, Cowen S, O'Sullivan DM, Bushell CA, Goenaga-Infante H, Foy CA, Woolford AJ, Parkes H, Huggett JF, Devonshire AS. Whale AS, et al. Clin Chem. 2018 Sep;64(9):1296-1307. doi: 10.1373/clinchem.2017.285478. Epub 2018 Jun 14. Clin Chem. 2018. PMID: 29903874
Pushing the Envelope with Clinical Use of Digital PCR.
Huggett JF, Devonshire AS, Whale AS, Cowen S, Foy CA. Huggett JF, et al. Among authors: whale as. Clin Chem. 2021 Jul 6;67(7):921-923. doi: 10.1093/clinchem/hvab082. Clin Chem. 2021. PMID: 34120171 No abstract available.
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