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Embracing Complexity beyond Systems Medicine: A New Approach to Chronic Immune Disorders.
Te Velde AA, Bezema T, van Kampen AH, Kraneveld AD, 't Hart BA, van Middendorp H, Hack EC, van Montfrans JM, Belzer C, Jans-Beken L, Pieters RH, Knipping K, Huber M, Boots AM, Garssen J, Radstake TR, Evers AW, Prakken BJ, Joosten I. Te Velde AA, et al. Among authors: van middendorp h, van kampen ah, van montfrans jm. Front Immunol. 2016 Dec 12;7:587. doi: 10.3389/fimmu.2016.00587. eCollection 2016. Front Immunol. 2016. PMID: 28018353 Free PMC article.
Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing.
Reshetova P, van Schaik BD, Klarenbeek PL, Doorenspleet ME, Esveldt RE, Tak PP, Guikema JE, de Vries N, van Kampen AH. Reshetova P, et al. Among authors: van kampen ah, van schaik bd. Front Immunol. 2017 Mar 6;8:221. doi: 10.3389/fimmu.2017.00221. eCollection 2017. Front Immunol. 2017. PMID: 28321219 Free PMC article.
Taking Bioinformatics to Systems Medicine.
van Kampen AH, Moerland PD. van Kampen AH, et al. Methods Mol Biol. 2016;1386:17-41. doi: 10.1007/978-1-4939-3283-2_2. Methods Mol Biol. 2016. PMID: 26677177 Free PMC article. Review.
Multiscale Modeling of Germinal Center Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells Differentiation as Regulated by Antigen Affinity-Based Tfh Cell Help.
Merino Tejero E, Lashgari D, García-Valiente R, Gao X, Crauste F, Robert PA, Meyer-Hermann M, Martínez MR, van Ham SM, Guikema JEJ, Hoefsloot H, van Kampen AHC. Merino Tejero E, et al. Front Immunol. 2021 Feb 5;11:620716. doi: 10.3389/fimmu.2020.620716. eCollection 2020. Front Immunol. 2021. PMID: 33613551 Free PMC article.
Coupled Antigen and BLIMP1 Asymmetric Division With a Large Segregation Between Daughter Cells Recapitulates the Temporal Transition From Memory B Cells to Plasma Cells and a DZ-to-LZ Ratio in the Germinal Center.
Merino Tejero E, Lashgari D, García-Valiente R, He J, Robert PA, Meyer-Hermann M, Guikema JEJ, Hoefsloot H, van Kampen AHC. Merino Tejero E, et al. Front Immunol. 2021 Aug 17;12:716240. doi: 10.3389/fimmu.2021.716240. eCollection 2021. Front Immunol. 2021. PMID: 34484219 Free PMC article.
TCRβ clones in muscle tissue share structural features in patients with idiopathic inflammatory myopathy and are associated with disease activity.
Anang DC, Walter HAW, Lim J, Niewold ITG, van der Weele L, Aronica E, Eftimov F, Raaphorst J, van Schaik BDC, van Kampen AHC, van der Kooi AJ, de Vries N. Anang DC, et al. Among authors: van kampen ahc. Front Immunol. 2024 Jan 10;14:1279055. doi: 10.3389/fimmu.2023.1279055. eCollection 2023. Front Immunol. 2024. PMID: 38268914 Free PMC article.
Human T-cell memory consists mainly of unexpanded clones.
Klarenbeek PL, Tak PP, van Schaik BD, Zwinderman AH, Jakobs ME, Zhang Z, van Kampen AH, van Lier RA, Baas F, de Vries N. Klarenbeek PL, et al. Among authors: van kampen ah, van lier ra, van schaik bd. Immunol Lett. 2010 Sep 6;133(1):42-8. doi: 10.1016/j.imlet.2010.06.011. Epub 2010 Jul 16. Immunol Lett. 2010. PMID: 20621124
125 results