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HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3.
Gringhuis SI, Hertoghs N, Kaptein TM, Zijlstra-Willems EM, Sarrami-Forooshani R, Sprokholt JK, van Teijlingen NH, Kootstra NA, Booiman T, van Dort KA, Ribeiro CM, Drewniak A, Geijtenbeek TB. Gringhuis SI, et al. Nat Immunol. 2017 Feb;18(2):225-235. doi: 10.1038/ni.3647. Epub 2016 Dec 26. Nat Immunol. 2017. PMID: 28024153
Human immature Langerhans cells restrict CXCR4-using HIV-1 transmission.
Sarrami-Forooshani R, Mesman AW, van Teijlingen NH, Sprokholt JK, van der Vlist M, Ribeiro CM, Geijtenbeek TB. Sarrami-Forooshani R, et al. Retrovirology. 2014 Jul 2;11:52. doi: 10.1186/1742-4690-11-52. Retrovirology. 2014. PMID: 24990163 Free PMC article.
Vaginal bacterium Prevotella timonensis turns protective Langerhans cells into HIV-1 reservoirs for virus dissemination.
van Teijlingen NH, Helgers LC, Sarrami-Forooshani R, Zijlstra-Willems EM, van Hamme JL, Segui-Perez C, van Smoorenburg MY, Borgdorff H, van de Wijgert JH, van Leeuwen E, van der Post JA, Strijbis K, Ribeiro CM, Geijtenbeek TB. van Teijlingen NH, et al. Among authors: sarrami forooshani r. EMBO J. 2022 Oct 4;41(19):e110629. doi: 10.15252/embj.2022110629. Epub 2022 Aug 15. EMBO J. 2022. PMID: 35968812 Free PMC article.
Prevotella timonensis bacteria associated with vaginal dysbiosis enhance HIV-1 susceptibility of vaginal CD4+ T cells.
van Teijlingen NH, van Smoorenburg MY, Sarrami-Forooshani R, Zijlstra-Willems EM, van Hamme JL, Borgdorff H, van de Wijgert JH, van Leeuwen E, van der Post JAM, Strijbis K, Ribeiro CMS, Geijtenbeek TBH. van Teijlingen NH, et al. Among authors: sarrami forooshani r. J Infect Dis. 2024 Apr 4:jiae166. doi: 10.1093/infdis/jiae166. Online ahead of print. J Infect Dis. 2024. PMID: 38573164
27 results