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"Marker of Self" CD47 on lentiviral vectors decreases macrophage-mediated clearance and increases delivery to SIRPA-expressing lung carcinoma tumors.
Mol Ther Methods Clin Dev. 2016 Dec 7;3:16080. doi: 10.1038/mtm.2016.80. eCollection 2016.
Mol Ther Methods Clin Dev. 2016.
PMID: 28053997
Free PMC article.
Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific 'Marker of Self' CD47, and target physical properties.
Sosale NG, Spinler KR, Alvey C, Discher DE.
Sosale NG, et al.
Curr Opin Immunol. 2015 Aug;35:107-12. doi: 10.1016/j.coi.2015.06.013. Epub 2015 Jul 13.
Curr Opin Immunol. 2015.
PMID: 26172292
Free PMC article.
Review.
Item in Clipboard
Marker-of-self becomes marker-of-senescence.
Sosale N, Discher DE.
Sosale N, et al.
Blood. 2012 Jun 7;119(23):5343-4. doi: 10.1182/blood-2012-04-418608.
Blood. 2012.
PMID: 22679336
Free article.
No abstract available.
Item in Clipboard
Cell rigidity and shape override CD47's "self"-signaling in phagocytosis by hyperactivating myosin-II.
Sosale NG, Rouhiparkouhi T, Bradshaw AM, Dimova R, Lipowsky R, Discher DE.
Sosale NG, et al.
Blood. 2015 Jan 15;125(3):542-52. doi: 10.1182/blood-2014-06-585299. Epub 2014 Nov 19.
Blood. 2015.
PMID: 25411427
Free PMC article.
Item in Clipboard
Cell signaling regulation by protein phosphorylation: a multivariate, heterogeneous, and context-dependent process.
Day EK, Sosale NG, Lazzara MJ.
Day EK, et al. Among authors: sosale ng.
Curr Opin Biotechnol. 2016 Aug;40:185-192. doi: 10.1016/j.copbio.2016.06.005. Epub 2016 Jul 6.
Curr Opin Biotechnol. 2016.
PMID: 27393828
Free PMC article.
Review.
Item in Clipboard
Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling.
Day EK, Sosale NG, Xiao A, Zhong Q, Purow B, Lazzara MJ.
Day EK, et al. Among authors: sosale ng.
Cell Rep. 2020 Mar 10;30(10):3383-3396.e7. doi: 10.1016/j.celrep.2020.02.014.
Cell Rep. 2020.
PMID: 32160544
Free PMC article.
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Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex.
D'Souza RS, Lim JY, Turgut A, Servage K, Zhang J, Orth K, Sosale NG, Lazzara MJ, Allegood J, Casanova JE.
D'Souza RS, et al. Among authors: sosale ng.
Elife. 2020 Apr 1;9:e54113. doi: 10.7554/eLife.54113.
Elife. 2020.
PMID: 32234213
Free PMC article.
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CX-5461 Treatment Leads to Cytosolic DNA-Mediated STING Activation in Ovarian Cancer.
Cornelison R, Biswas K, Llaneza DC, Harris AR, Sosale NG, Lazzara MJ, Landen CN.
Cornelison R, et al. Among authors: sosale ng.
Cancers (Basel). 2021 Oct 9;13(20):5056. doi: 10.3390/cancers13205056.
Cancers (Basel). 2021.
PMID: 34680204
Free PMC article.
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