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CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus.
Faridi MH, Khan SQ, Zhao W, Lee HW, Altintas MM, Zhang K, Kumar V, Armstrong AR, Carmona-Rivera C, Dorschner JM, Schnaith AM, Li X, Ghodke-Puranik Y, Moore E, Purmalek M, Irizarry-Caro J, Zhang T, Day R, Stoub D, Hoffmann V, Khaliqdina SJ, Bhargava P, Santander AM, Torroella-Kouri M, Issac B, Cimbaluk DJ, Zloza A, Prabhakar R, Deep S, Jolly M, Koh KH, Reichner JS, Bradshaw EM, Chen J, Moita LF, Yuen PS, Li Tsai W, Singh B, Reiser J, Nath SK, Niewold TB, Vazquez-Padron RI, Kaplan MJ, Gupta V. Faridi MH, et al. Among authors: dorschner jm. J Clin Invest. 2017 Apr 3;127(4):1271-1283. doi: 10.1172/JCI88442. Epub 2017 Mar 6. J Clin Invest. 2017. PMID: 28263189 Free PMC article.
Novel genetic associations with interferon in systemic lupus erythematosus identified by replication and fine-mapping of trait-stratified genome-wide screen.
Ghodke-Puranik Y, Imgruet M, Dorschner JM, Shrestha P, McCoy K, Kelly JA, Marion M, Guthridge JM, Langefeld CD, Harley JB, James JA, Sivils KL, Niewold TB. Ghodke-Puranik Y, et al. Among authors: dorschner jm. Cytokine. 2020 Aug;132:154631. doi: 10.1016/j.cyto.2018.12.014. Epub 2019 Jan 24. Cytokine. 2020. PMID: 30685201 Free PMC article.
Lupus-Associated Functional Polymorphism in PNP Causes Cell Cycle Abnormalities and Interferon Pathway Activation in Human Immune Cells.
Ghodke-Puranik Y, Dorschner JM, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Eliopoulos E, Zervou MI, Goulielmos GN, Jensen MA, Niewold TB. Ghodke-Puranik Y, et al. Among authors: dorschner jm. Arthritis Rheumatol. 2017 Dec;69(12):2328-2337. doi: 10.1002/art.40304. Epub 2017 Nov 9. Arthritis Rheumatol. 2017. PMID: 28859258 Free PMC article.
Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.
Kariuki SN, Ghodke-Puranik Y, Dorschner JM, Chrabot BS, Kelly JA, Tsao BP, Kimberly RP, Alarcón-Riquelme ME, Jacob CO, Criswell LA, Sivils KL, Langefeld CD, Harley JB, Skol AD, Niewold TB. Kariuki SN, et al. Among authors: dorschner jm. Genes Immun. 2015 Jan-Feb;16(1):15-23. doi: 10.1038/gene.2014.57. Epub 2014 Oct 23. Genes Immun. 2015. PMID: 25338677 Free PMC article.
Type I Interferon Predicts an Alternate Immune System Phenotype in Systemic Lupus Erythematosus.
Thanarajasingam U, Muppirala AN, Jensen MA, Ghodke-Puranik Y, Dorschner JM, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold TB. Thanarajasingam U, et al. Among authors: dorschner jm. ACR Open Rheumatol. 2019 Aug 19;1(8):499-506. doi: 10.1002/acr2.11073. eCollection 2019 Oct. ACR Open Rheumatol. 2019. PMID: 31777831 Free PMC article.
Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes.
Ghodke-Puranik Y, Jin Z, Zimmerman KD, Ainsworth HC, Fan W, Jensen MA, Dorschner JM, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Langefeld CD, Niewold TB. Ghodke-Puranik Y, et al. Among authors: dorschner jm. Arthritis Res Ther. 2021 Nov 30;23(1):290. doi: 10.1186/s13075-021-02660-2. Arthritis Res Ther. 2021. PMID: 34847931 Free PMC article.
Brief Report: A Novel ELANE Mutation Associated With Inflammatory Arthritis, Defective NETosis, and Recurrent Parvovirus Infection.
Thanarajasingam U, Jensen MA, Dorschner JM, Wampler Muskardin T, Ghodke-Puranik Y, Purmalek M, Eliopoulos E, Zervou MI, Goulielmos GN, Howard M, Kaplan MJ, Niewold TB. Thanarajasingam U, et al. Among authors: dorschner jm. Arthritis Rheumatol. 2017 Dec;69(12):2396-2401. doi: 10.1002/art.40314. Epub 2017 Nov 8. Arthritis Rheumatol. 2017. PMID: 28881492 Free PMC article.
18 results