Widman DG - Search Results

1

A Reverse Genetics Platform That Spans the Zika Virus Family Tree.

Widman DG, Young E, Yount BL, Plante KS, Gallichotte EN, Carbaugh DL, Peck KM, Plante J, Swanstrom J, Heise MT, Lazear HM, Baric RS. Widman DG, et al. mBio. 2017 Mar 7;8(2):e02014-16. doi: 10.1128/mBio.02014-16. mBio. 2017. PMID: 28270583 Free PMC article.

2

Functional Transplant of a Dengue Virus Serotype 3 (DENV3)-Specific Human Monoclonal Antibody Epitope into DENV1.

Messer WB, Yount BL, Royal SR, de Alwis R, Widman DG, Smith SA, Crowe JE Jr, Pfaff JM, Kahle KM, Doranz BJ, Ibarra KD, Harris E, de Silva AM, Baric RS. Messer WB, et al. Among authors: widman dg. J Virol. 2016 Apr 29;90(10):5090-5097. doi: 10.1128/JVI.00155-16. Print 2016 May 15. J Virol. 2016. PMID: 26962223 Free PMC article.

3

Neutralization mechanism of a highly potent antibody against Zika virus.

Zhang S, Kostyuchenko VA, Ng TS, Lim XN, Ooi JSG, Lambert S, Tan TY, Widman DG, Shi J, Baric RS, Lok SM. Zhang S, et al. Among authors: widman dg. Nat Commun. 2016 Nov 24;7:13679. doi: 10.1038/ncomms13679. Nat Commun. 2016. PMID: 27882950 Free PMC article.

4

Epitope Addition and Ablation via Manipulation of a Dengue Virus Serotype 1 Infectious Clone.

Gallichotte EN, Menachery VD, Yount BL Jr, Widman DG, Dinnon KH 3rd, Hartman S, de Silva AM, Baric RS. Gallichotte EN, et al. Among authors: widman dg. mSphere. 2017 Feb 22;2(1):e00380-16. doi: 10.1128/mSphere.00380-16. eCollection 2017 Jan-Feb. mSphere. 2017. PMID: 28251184 Free PMC article.

5

Transplantation of a quaternary structure neutralizing antibody epitope from dengue virus serotype 3 into serotype 4.

Widman DG, Young E, Nivarthi U, Swanstrom JA, Royal SR, Yount BL, Debbink K, Begley M, Marcet S, Durbin A, de Silva AM, Messer WB, Baric RS. Widman DG, et al. Sci Rep. 2017 Dec 7;7(1):17169. doi: 10.1038/s41598-017-17355-5. Sci Rep. 2017. PMID: 29215033 Free PMC article.

6

Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain.

Adams Waldorf KM, Nelson BR, Stencel-Baerenwald JE, Studholme C, Kapur RP, Armistead B, Walker CL, Merillat S, Vornhagen J, Tisoncik-Go J, Baldessari A, Coleman M, Dighe MK, Shaw DWW, Roby JA, Santana-Ufret V, Boldenow E, Li J, Gao X, Davis MA, Swanstrom JA, Jensen K, Widman DG, Baric RS, Medwid JT, Hanley KA, Ogle J, Gough GM, Lee W, English C, Durning WM, Thiel J, Gatenby C, Dewey EC, Fairgrieve MR, Hodge RD, Grant RF, Kuller L, Dobyns WB, Hevner RF, Gale M Jr, Rajagopal L. Adams Waldorf KM, et al. Among authors: widman dg. Nat Med. 2018 Mar;24(3):368-374. doi: 10.1038/nm.4485. Epub 2018 Feb 5. Nat Med. 2018. PMID: 29400709 Free PMC article.

7

Human dengue virus serotype 2 neutralizing antibodies target two distinct quaternary epitopes.

Gallichotte EN, Baric TJ, Yount BL Jr, Widman DG, Durbin A, Whitehead S, Baric RS, de Silva AM. Gallichotte EN, et al. Among authors: widman dg. PLoS Pathog. 2018 Feb 26;14(2):e1006934. doi: 10.1371/journal.ppat.1006934. eCollection 2018 Feb. PLoS Pathog. 2018. PMID: 29481552 Free PMC article.

8

Analyzing the Human Serum Antibody Responses to a Live Attenuated Tetravalent Dengue Vaccine Candidate.

Swanstrom JA, Henein S, Plante JA, Yount BL, Widman DG, Gallichotte EN, Dean HJ, Osorio JE, Partidos CD, de Silva AM, Baric RS. Swanstrom JA, et al. Among authors: widman dg. J Infect Dis. 2018 May 25;217(12):1932-1941. doi: 10.1093/infdis/jiy063. J Infect Dis. 2018. PMID: 29800370 Free PMC article. Clinical Trial.

9

Genetic Variation between Dengue Virus Type 4 Strains Impacts Human Antibody Binding and Neutralization.

Gallichotte EN, Baric TJ, Nivarthi U, Delacruz MJ, Graham R, Widman DG, Yount BL, Durbin AP, Whitehead SS, de Silva AM, Baric RS. Gallichotte EN, et al. Among authors: widman dg. Cell Rep. 2018 Oct 30;25(5):1214-1224. doi: 10.1016/j.celrep.2018.10.006. Cell Rep. 2018. PMID: 30380413 Free PMC article.

10

Beyond Neutralizing Antibody Levels: The Epitope Specificity of Antibodies Induced by National Institutes of Health Monovalent Dengue Virus Vaccines.

Swanstrom JA, Nivarthi UK, Patel B, Delacruz MJ, Yount B, Widman DG, Durbin AP, Whitehead SS, De Silva AM, Baric RS. Swanstrom JA, et al. Among authors: widman dg. J Infect Dis. 2019 Jun 19;220(2):219-227. doi: 10.1093/infdis/jiz109. J Infect Dis. 2019. PMID: 30895307 Free PMC article.

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