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HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.
Davies H, Glodzik D, Morganella S, Yates LR, Staaf J, Zou X, Ramakrishna M, Martin S, Boyault S, Sieuwerts AM, Simpson PT, King TA, Raine K, Eyfjord JE, Kong G, Borg Å, Birney E, Stunnenberg HG, van de Vijver MJ, Børresen-Dale AL, Martens JW, Span PN, Lakhani SR, Vincent-Salomon A, Sotiriou C, Tutt A, Thompson AM, Van Laere S, Richardson AL, Viari A, Campbell PJ, Stratton MR, Nik-Zainal S. Davies H, et al. Among authors: simpson pt. Nat Med. 2017 Apr;23(4):517-525. doi: 10.1038/nm.4292. Epub 2017 Mar 13. Nat Med. 2017. PMID: 28288110 Free PMC article.
Molecular evolution of breast cancer.
Simpson PT, Reis-Filho JS, Gale T, Lakhani SR. Simpson PT, et al. J Pathol. 2005 Jan;205(2):248-54. doi: 10.1002/path.1691. J Pathol. 2005. PMID: 15641021 Review.
Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis.
Reis-Filho JS, Milanezi F, Carvalho S, Simpson PT, Steele D, Savage K, Lambros MB, Pereira EM, Nesland JM, Lakhani SR, Schmitt FC. Reis-Filho JS, et al. Among authors: simpson pt. Breast Cancer Res. 2005;7(6):R1028-35. doi: 10.1186/bcr1341. Epub 2005 Oct 25. Breast Cancer Res. 2005. PMID: 16280056 Free PMC article.
FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas.
Reis-Filho JS, Simpson PT, Turner NC, Lambros MB, Jones C, Mackay A, Grigoriadis A, Sarrio D, Savage K, Dexter T, Iravani M, Fenwick K, Weber B, Hardisson D, Schmitt FC, Palacios J, Lakhani SR, Ashworth A. Reis-Filho JS, et al. Among authors: simpson pt. Clin Cancer Res. 2006 Nov 15;12(22):6652-62. doi: 10.1158/1078-0432.CCR-06-1164. Clin Cancer Res. 2006. PMID: 17121884
Aberrant expression of E-cadherin in lobular carcinomas of the breast.
Da Silva L, Parry S, Reid L, Keith P, Waddell N, Kossai M, Clarke C, Lakhani SR, Simpson PT. Da Silva L, et al. Among authors: simpson pt. Am J Surg Pathol. 2008 May;32(5):773-83. doi: 10.1097/PAS.0b013e318158d6c5. Am J Surg Pathol. 2008. PMID: 18379416
172 results