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Gpr124 is essential for blood-brain barrier integrity in central nervous system disease.
Chang J, Mancuso MR, Maier C, Liang X, Yuki K, Yang L, Kwong JW, Wang J, Rao V, Vallon M, Kosinski C, Zhang JJ, Mah AT, Xu L, Li L, Gholamin S, Reyes TF, Li R, Kuhnert F, Han X, Yuan J, Chiou SH, Brettman AD, Daly L, Corney DC, Cheshier SH, Shortliffe LD, Wu X, Snyder M, Chan P, Giffard RG, Chang HY, Andreasson K, Kuo CJ. Chang J, et al. Among authors: snyder m. Nat Med. 2017 Apr;23(4):450-460. doi: 10.1038/nm.4309. Epub 2017 Mar 13. Nat Med. 2017. PMID: 28288111 Free PMC article.
Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal.
Yan KS, Janda CY, Chang J, Zheng GXY, Larkin KA, Luca VC, Chia LA, Mah AT, Han A, Terry JM, Ootani A, Roelf K, Lee M, Yuan J, Li X, Bolen CR, Wilhelmy J, Davies PS, Ueno H, von Furstenberg RJ, Belgrader P, Ziraldo SB, Ordonez H, Henning SJ, Wong MH, Snyder MP, Weissman IL, Hsueh AJ, Mikkelsen TS, Garcia KC, Kuo CJ. Yan KS, et al. Among authors: snyder mp. Nature. 2017 May 11;545(7653):238-242. doi: 10.1038/nature22313. Epub 2017 May 3. Nature. 2017. PMID: 28467820 Free PMC article.
Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation.
Rubin AJ, Barajas BC, Furlan-Magaril M, Lopez-Pajares V, Mumbach MR, Howard I, Kim DS, Boxer LD, Cairns J, Spivakov M, Wingett SW, Shi M, Zhao Z, Greenleaf WJ, Kundaje A, Snyder M, Chang HY, Fraser P, Khavari PA. Rubin AJ, et al. Among authors: snyder m. Nat Genet. 2017 Oct;49(10):1522-1528. doi: 10.1038/ng.3935. Epub 2017 Aug 14. Nat Genet. 2017. PMID: 28805829 Free PMC article.
Challenges and recommendations for epigenomics in precision health.
Carter AC, Chang HY, Church G, Dombkowski A, Ecker JR, Gil E, Giresi PG, Greely H, Greenleaf WJ, Hacohen N, He C, Hill D, Ko J, Kohane I, Kundaje A, Palmer M, Snyder MP, Tung J, Urban A, Vidal M, Wong W. Carter AC, et al. Among authors: snyder mp. Nat Biotechnol. 2017 Dec 8;35(12):1128-1132. doi: 10.1038/nbt.4030. Nat Biotechnol. 2017. PMID: 29220033 Free PMC article. No abstract available.
Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation.
Minhas PS, Liu L, Moon PK, Joshi AU, Dove C, Mhatre S, Contrepois K, Wang Q, Lee BA, Coronado M, Bernstein D, Snyder MP, Migaud M, Majeti R, Mochly-Rosen D, Rabinowitz JD, Andreasson KI. Minhas PS, et al. Among authors: snyder mp. Nat Immunol. 2019 Jan;20(1):50-63. doi: 10.1038/s41590-018-0255-3. Epub 2018 Nov 26. Nat Immunol. 2019. PMID: 30478397 Free PMC article.
HAT1 Coordinates Histone Production and Acetylation via H4 Promoter Binding.
Gruber JJ, Geller B, Lipchik AM, Chen J, Salahudeen AA, Ram AN, Ford JM, Kuo CJ, Snyder MP. Gruber JJ, et al. Among authors: snyder mp. Mol Cell. 2019 Aug 22;75(4):711-724.e5. doi: 10.1016/j.molcel.2019.05.034. Epub 2019 Jul 2. Mol Cell. 2019. PMID: 31278053 Free PMC article.
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy.
Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, Rhee JW, Churko JM, Chaudhary R, Chour T, Wang PJ, Snyder MP, Chang HY, Karakikes I, Wu JC. Lee J, et al. Among authors: snyder mp. Nature. 2019 Aug;572(7769):335-340. doi: 10.1038/s41586-019-1406-x. Epub 2019 Jul 17. Nature. 2019. PMID: 31316208 Free PMC article.
2,297 results