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Gpr124 is essential for blood-brain barrier integrity in central nervous system disease.
Chang J, Mancuso MR, Maier C, Liang X, Yuki K, Yang L, Kwong JW, Wang J, Rao V, Vallon M, Kosinski C, Zhang JJ, Mah AT, Xu L, Li L, Gholamin S, Reyes TF, Li R, Kuhnert F, Han X, Yuan J, Chiou SH, Brettman AD, Daly L, Corney DC, Cheshier SH, Shortliffe LD, Wu X, Snyder M, Chan P, Giffard RG, Chang HY, Andreasson K, Kuo CJ. Chang J, et al. Among authors: yang l. Nat Med. 2017 Apr;23(4):450-460. doi: 10.1038/nm.4309. Epub 2017 Mar 13. Nat Med. 2017. PMID: 28288111 Free PMC article.
The Cerebroventricular Environment Modifies CAR T Cells for Potent Activity against Both Central Nervous System and Systemic Lymphoma.
Wang X, Huynh C, Urak R, Weng L, Walter M, Lim L, Vyas V, Chang WC, Aguilar B, Brito A, Sarkissian A, Bandara NA, Yang L, Wang J, Wu X, Zhang J, Priceman SJ, Qin H, Kwak LW, Budde LE, Thomas SH, Clark MC, Popplewell L, Siddiqi T, Brown CE, Forman SJ. Wang X, et al. Among authors: yang l. Cancer Immunol Res. 2021 Jan;9(1):75-88. doi: 10.1158/2326-6066.CIR-20-0236. Epub 2020 Oct 22. Cancer Immunol Res. 2021. PMID: 33093217 Free PMC article.
ERα-mediated cell cycle progression is an important requisite for CDK4/6 inhibitor response in HR+ breast cancer.
Petrossian K, Kanaya N, Lo C, Hsu PY, Nguyen D, Yang L, Yang L, Warden C, Wu X, Pillai R, Bernal L, Huang CS, Kruper L, Yuan Y, Somlo G, Mortimer J, Chen S. Petrossian K, et al. Among authors: yang l. Oncotarget. 2018 Jun 12;9(45):27736-27751. doi: 10.18632/oncotarget.25552. eCollection 2018 Jun 12. Oncotarget. 2018. PMID: 29963233 Free PMC article.
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