Haining WN - Search Results

1

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity.

Juneja VR, McGuire KA, Manguso RT, LaFleur MW, Collins N, Haining WN, Freeman GJ, Sharpe AH. Juneja VR, et al. Among authors: haining wn. J Exp Med. 2017 Apr 3;214(4):895-904. doi: 10.1084/jem.20160801. Epub 2017 Mar 16. J Exp Med. 2017. PMID: 28302645 Free PMC article.

2

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

Blackburn SD, Shin H, Haining WN, Zou T, Workman CJ, Polley A, Betts MR, Freeman GJ, Vignali DA, Wherry EJ. Blackburn SD, et al. Among authors: haining wn. Nat Immunol. 2009 Jan;10(1):29-37. doi: 10.1038/ni.1679. Epub 2008 Nov 30. Nat Immunol. 2009. PMID: 19043418 Free PMC article.

3

Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF.

Quigley M, Pereyra F, Nilsson B, Porichis F, Fonseca C, Eichbaum Q, Julg B, Jesneck JL, Brosnahan K, Imam S, Russell K, Toth I, Piechocka-Trocha A, Dolfi D, Angelosanto J, Crawford A, Shin H, Kwon DS, Zupkosky J, Francisco L, Freeman GJ, Wherry EJ, Kaufmann DE, Walker BD, Ebert B, Haining WN. Quigley M, et al. Among authors: haining wn. Nat Med. 2010 Oct;16(10):1147-51. doi: 10.1038/nm.2232. Epub 2010 Oct 3. Nat Med. 2010. PMID: 20890291 Free PMC article.

4

Phenotype, function, and gene expression profiles of programmed death-1(hi) CD8 T cells in healthy human adults.

Duraiswamy J, Ibegbu CC, Masopust D, Miller JD, Araki K, Doho GH, Tata P, Gupta S, Zilliox MJ, Nakaya HI, Pulendran B, Haining WN, Freeman GJ, Ahmed R. Duraiswamy J, et al. Among authors: haining wn. J Immunol. 2011 Apr 1;186(7):4200-12. doi: 10.4049/jimmunol.1001783. Epub 2011 Mar 7. J Immunol. 2011. PMID: 21383243 Free PMC article.

5

Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load.

West EE, Youngblood B, Tan WG, Jin HT, Araki K, Alexe G, Konieczny BT, Calpe S, Freeman GJ, Terhorst C, Haining WN, Ahmed R. West EE, et al. Among authors: haining wn. Immunity. 2011 Aug 26;35(2):285-98. doi: 10.1016/j.immuni.2011.05.017. Immunity. 2011. PMID: 21856186 Free PMC article.

6

CD28 costimulation regulates genome-wide effects on alternative splicing.

Butte MJ, Lee SJ, Jesneck J, Keir ME, Haining WN, Sharpe AH. Butte MJ, et al. Among authors: haining wn. PLoS One. 2012;7(6):e40032. doi: 10.1371/journal.pone.0040032. Epub 2012 Jun 29. PLoS One. 2012. PMID: 22768209 Free PMC article.

7

Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8+ T-cell effector differentiation.

Godec J, Cowley GS, Barnitz RA, Alkan O, Root DE, Sharpe AH, Haining WN. Godec J, et al. Among authors: haining wn. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):512-7. doi: 10.1073/pnas.1413291112. Epub 2014 Dec 29. Proc Natl Acad Sci U S A. 2015. PMID: 25548173 Free PMC article.

8

CD39 Expression Identifies Terminally Exhausted CD8+ T Cells.

Gupta PK, Godec J, Wolski D, Adland E, Yates K, Pauken KE, Cosgrove C, Ledderose C, Junger WG, Robson SC, Wherry EJ, Alter G, Goulder PJ, Klenerman P, Sharpe AH, Lauer GM, Haining WN. Gupta PK, et al. Among authors: haining wn. PLoS Pathog. 2015 Oct 20;11(10):e1005177. doi: 10.1371/journal.ppat.1005177. eCollection 2015 Oct. PLoS Pathog. 2015. PMID: 26485519 Free PMC article.

9

Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells.

Provine NM, Larocca RA, Aid M, Penaloza-MacMaster P, Badamchi-Zadeh A, Borducchi EN, Yates KB, Abbink P, Kirilova M, Ng'ang'a D, Bramson J, Haining WN, Barouch DH. Provine NM, et al. Among authors: haining wn. J Immunol. 2016 Sep 1;197(5):1809-22. doi: 10.4049/jimmunol.1600591. Epub 2016 Jul 22. J Immunol. 2016. PMID: 27448585 Free PMC article.

10

Suppression by T_FR cells leads to durable and selective inhibition of B cell effector function.

Sage PT, Ron-Harel N, Juneja VR, Sen DR, Maleri S, Sungnak W, Kuchroo VK, Haining WN, Chevrier N, Haigis M, Sharpe AH. Sage PT, et al. Among authors: haining wn. Nat Immunol. 2016 Dec;17(12):1436-1446. doi: 10.1038/ni.3578. Epub 2016 Oct 3. Nat Immunol. 2016. PMID: 27695002 Free PMC article.

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