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Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals.
Levine MS, Bakker B, Boeckx B, Moyett J, Lu J, Vitre B, Spierings DC, Lansdorp PM, Cleveland DW, Lambrechts D, Foijer F, Holland AJ. Levine MS, et al. Among authors: spierings dc. Dev Cell. 2017 Feb 6;40(3):313-322.e5. doi: 10.1016/j.devcel.2016.12.022. Epub 2017 Jan 26. Dev Cell. 2017. PMID: 28132847 Free PMC article.
Non-random Mis-segregation of Human Chromosomes.
Worrall JT, Tamura N, Mazzagatti A, Shaikh N, van Lingen T, Bakker B, Spierings DCJ, Vladimirou E, Foijer F, McClelland SE. Worrall JT, et al. Cell Rep. 2018 Jun 12;23(11):3366-3380. doi: 10.1016/j.celrep.2018.05.047. Cell Rep. 2018. PMID: 29898405 Free PMC article.
Extra centrosomes delay DNA damage-driven tumorigenesis.
Braun VZ, Karbon G, Schuler F, Schapfl MA, Weiss JG, Petermann PY, Spierings DCJ, Tijhuis AE, Foijer F, Labi V, Villunger A. Braun VZ, et al. Among authors: spierings dcj. Sci Adv. 2024 Mar 29;10(13):eadk0564. doi: 10.1126/sciadv.adk0564. Epub 2024 Mar 29. Sci Adv. 2024. PMID: 38552015 Free PMC article.
Drug-resilient Cancer Cell Phenotype Is Acquired via Polyploidization Associated with Early Stress Response Coupled to HIF2α Transcriptional Regulation.
Carroll C, Manaprasertsak A, Boffelli Castro A, van den Bos H, Spierings DCJ, Wardenaar R, Bukkuri A, Engström N, Baratchart E, Yang M, Biloglav A, Cornwallis CK, Johansson B, Hagerling C, Arsenian-Henriksson M, Paulsson K, Amend SR, Mohlin S, Foijer F, McIntyre A, Pienta KJ, Hammarlund EU. Carroll C, et al. Among authors: spierings dcj. Cancer Res Commun. 2024 Mar 7;4(3):691-705. doi: 10.1158/2767-9764.CRC-23-0396. Cancer Res Commun. 2024. PMID: 38385626 Free PMC article.
Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization.
Scelfo A, Barra V, Abdennur N, Spracklin G, Busato F, Salinas-Luypaert C, Bonaiti E, Velasco G, Bonhomme F, Chipont A, Tijhuis AE, Spierings DCJ, Guérin C, Arimondo P, Francastel C, Foijer F, Tost J, Mirny L, Fachinetti D. Scelfo A, et al. Among authors: spierings dcj. J Cell Biol. 2024 Apr 1;223(4):e202307026. doi: 10.1083/jcb.202307026. Epub 2024 Feb 20. J Cell Biol. 2024. PMID: 38376465
88 results