Schoepfer J - Search Results

1

The allosteric inhibitor ABL001 enables dual targeting of BCR-ABL1.

Wylie AA, Schoepfer J, Jahnke W, Cowan-Jacob SW, Loo A, Furet P, Marzinzik AL, Pelle X, Donovan J, Zhu W, Buonamici S, Hassan AQ, Lombardo F, Iyer V, Palmer M, Berellini G, Dodd S, Thohan S, Bitter H, Branford S, Ross DM, Hughes TP, Petruzzelli L, Vanasse KG, Warmuth M, Hofmann F, Keen NJ, Sellers WR. Wylie AA, et al. Among authors: schoepfer j. Nature. 2017 Mar 30;543(7647):733-737. doi: 10.1038/nature21702. Epub 2017 Mar 22. Nature. 2017. PMID: 28329763

2

Potent antagonists of the SH2 domain of Grb2: optimization of the X+1 position of 3-amino-Z-Tyr(PO3H2)-X+1-Asn-NH2.

García-Echeverría C, Furet P, Gay B, Fretz H, Rahuel J, Schoepfer J, Caravatti G. García-Echeverría C, et al. Among authors: schoepfer j. J Med Chem. 1998 May 21;41(11):1741-4. doi: 10.1021/jm970856n. J Med Chem. 1998. PMID: 9599224 No abstract available.

3

Selective GRB2 SH2 inhibitors as anti-Ras therapy.

Gay B, Suarez S, Caravatti G, Furet P, Meyer T, Schoepfer J. Gay B, et al. Among authors: schoepfer j. Int J Cancer. 1999 Oct 8;83(2):235-41. doi: 10.1002/(sici)1097-0215(19991008)83:2<235::aid-ijc15>3.0.co;2-b. Int J Cancer. 1999. PMID: 10471533 Free article.

4

Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product.

Soni R, Muller L, Furet P, Schoepfer J, Stephan C, Zumstein-Mecker S, Fretz H, Chaudhuri B. Soni R, et al. Among authors: schoepfer j. Biochem Biophys Res Commun. 2000 Sep 7;275(3):877-84. doi: 10.1006/bbrc.2000.3349. Biochem Biophys Res Commun. 2000. PMID: 10973815

5

Structure-based design of compounds inhibiting Grb2-SH2 mediated protein-protein interactions in signal transduction pathways.

Fretz H, Furet P, Garcia-Echeverria C, Schoepfer J, Rahuel J. Fretz H, et al. Among authors: schoepfer j. Curr Pharm Des. 2000 Dec;6(18):1777-96. doi: 10.2174/1381612003398546. Curr Pharm Des. 2000. PMID: 11102562 Review.

6

Discovery of a potent and selective protein kinase CK2 inhibitor by high-throughput docking.

Vangrevelinghe E, Zimmermann K, Schoepfer J, Portmann R, Fabbro D, Furet P. Vangrevelinghe E, et al. Among authors: schoepfer j. J Med Chem. 2003 Jun 19;46(13):2656-62. doi: 10.1021/jm030827e. J Med Chem. 2003. PMID: 12801229

7

Entry into a new class of protein kinase inhibitors by pseudo ring design.

Furet P, Caravatti G, Guagnano V, Lang M, Meyer T, Schoepfer J. Furet P, et al. Among authors: schoepfer j. Bioorg Med Chem Lett. 2008 Feb 1;18(3):897-900. doi: 10.1016/j.bmcl.2007.12.041. Epub 2008 Jan 14. Bioorg Med Chem Lett. 2008. PMID: 18248988

8

Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue.

Chène P, Rudloff J, Schoepfer J, Furet P, Meier P, Qian Z, Schlaeppi JM, Schmitz R, Radimerski T. Chène P, et al. Among authors: schoepfer j. BMC Chem Biol. 2009 Jan 7;9:1. doi: 10.1186/1472-6769-9-1. BMC Chem Biol. 2009. PMID: 19128485 Free PMC article.

9

Discovery of a new class of catalytic topoisomerase II inhibitors targeting the ATP-binding site by structure based design. Part I.

Furet P, Schoepfer J, Radimerski T, Chène P. Furet P, et al. Among authors: schoepfer j. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4014-7. doi: 10.1016/j.bmcl.2009.06.034. Epub 2009 Jun 13. Bioorg Med Chem Lett. 2009. PMID: 19560355

10

A drug resistance screen using a selective MET inhibitor reveals a spectrum of mutations that partially overlap with activating mutations found in cancer patients.

Tiedt R, Degenkolbe E, Furet P, Appleton BA, Wagner S, Schoepfer J, Buck E, Ruddy DA, Monahan JE, Jones MD, Blank J, Haasen D, Drueckes P, Wartmann M, McCarthy C, Sellers WR, Hofmann F. Tiedt R, et al. Among authors: schoepfer j. Cancer Res. 2011 Aug 1;71(15):5255-64. doi: 10.1158/0008-5472.CAN-10-4433. Epub 2011 Jun 22. Cancer Res. 2011. PMID: 21697284

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

42 results

Search Page