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Reduced Nasal Viral Load and IFN Responses in Infants with Respiratory Syncytial Virus Bronchiolitis and Respiratory Failure.
Thwaites RS, Coates M, Ito K, Ghazaly M, Feather C, Abdulla F, Tunstall T, Jain P, Cass L, Rapeport G, Hansel TT, Nadel S, Openshaw P. Thwaites RS, et al. Among authors: cass l. Am J Respir Crit Care Med. 2018 Oct 15;198(8):1074-1084. doi: 10.1164/rccm.201712-2567OC. Am J Respir Crit Care Med. 2018. PMID: 29688024 Free PMC article.
Preclinical Characterization of PC786, an Inhaled Small-Molecule Respiratory Syncytial Virus L Protein Polymerase Inhibitor.
Coates M, Brookes D, Kim YI, Allen H, Fordyce EAF, Meals EA, Colley T, Ciana CL, Parra GF, Sherbukhin V, Stockwell JA, Thomas JC, Hunt SF, Anderson-Dring L, Onions ST, Cass L, Murray PJ, Ito K, Strong P, DeVincenzo JP, Rapeport G. Coates M, et al. Among authors: cass l. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00737-17. doi: 10.1128/AAC.00737-17. Print 2017 Sep. Antimicrob Agents Chemother. 2017. PMID: 28652242 Free PMC article.
Late therapeutic intervention with a respiratory syncytial virus L-protein polymerase inhibitor, PC786, on respiratory syncytial virus infection in human airway epithelium.
Brookes DW, Coates M, Allen H, Daly L, Constant S, Huang S, Hows M, Davis A, Cass L, Ayrton J, Knowles I, Strong P, Rapeport G, Ito K. Brookes DW, et al. Among authors: cass l. Br J Pharmacol. 2018 Jun;175(12):2520-2534. doi: 10.1111/bph.14221. Epub 2018 May 2. Br J Pharmacol. 2018. PMID: 29579332 Free PMC article.
149 results