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A new fate mapping system reveals context-dependent random or clonal expansion of microglia.
Tay TL, Mai D, Dautzenberg J, Fernández-Klett F, Lin G, Sagar, Datta M, Drougard A, Stempfl T, Ardura-Fabregat A, Staszewski O, Margineanu A, Sporbert A, Steinmetz LM, Pospisilik JA, Jung S, Priller J, Grün D, Ronneberger O, Prinz M. Tay TL, et al. Nat Neurosci. 2017 Jun;20(6):793-803. doi: 10.1038/nn.4547. Epub 2017 Apr 17. Nat Neurosci. 2017. PMID: 28414331
USP18 lack in microglia causes destructive interferonopathy of the mouse brain.
Goldmann T, Zeller N, Raasch J, Kierdorf K, Frenzel K, Ketscher L, Basters A, Staszewski O, Brendecke SM, Spiess A, Tay TL, Kreutz C, Timmer J, Mancini GM, Blank T, Fritz G, Biber K, Lang R, Malo D, Merkler D, Heikenwälder M, Knobeloch KP, Prinz M. Goldmann T, et al. Among authors: tay tl. EMBO J. 2015 Jun 12;34(12):1612-29. doi: 10.15252/embj.201490791. Epub 2015 Apr 20. EMBO J. 2015. PMID: 25896511 Free PMC article.
Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner.
Datta M, Staszewski O, Raschi E, Frosch M, Hagemeyer N, Tay TL, Blank T, Kreutzfeldt M, Merkler D, Ziegler-Waldkirch S, Matthias P, Meyer-Luehmann M, Prinz M. Datta M, et al. Among authors: tay tl. Immunity. 2018 Mar 20;48(3):514-529.e6. doi: 10.1016/j.immuni.2018.02.016. Epub 2018 Mar 13. Immunity. 2018. PMID: 29548672 Free article.
Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge.
Shemer A, Grozovski J, Tay TL, Tao J, Volaski A, Süß P, Ardura-Fabregat A, Gross-Vered M, Kim JS, David E, Chappell-Maor L, Thielecke L, Glass CK, Cornils K, Prinz M, Jung S. Shemer A, et al. Among authors: tay tl. Nat Commun. 2018 Dec 6;9(1):5206. doi: 10.1038/s41467-018-07548-5. Nat Commun. 2018. PMID: 30523248 Free PMC article.
38 results