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The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma.
Coulson R, Liew SH, Connelly AA, Yee NS, Deb S, Kumar B, Vargas AC, O'Toole SA, Parslow AC, Poh A, Putoczki T, Morrow RJ, Alorro M, Lazarus KA, Yeap EFW, Walton KL, Harrison CA, Hannan NJ, George AJ, Clyne CD, Ernst M, Allen AM, Chand AL. Coulson R, et al. Among authors: hannan nj. Oncotarget. 2017 Mar 21;8(12):18640-18656. doi: 10.18632/oncotarget.15553. Oncotarget. 2017. PMID: 28416734 Free PMC article.
Activating Transcription Factor 3 Is Reduced in Preeclamptic Placentas and Negatively Regulates sFlt-1 (Soluble fms-Like Tyrosine Kinase 1), Soluble Endoglin, and Proinflammatory Cytokines in Placenta.
Kaitu'u-Lino TJ, Brownfoot FC, Hastie R, Chand A, Cannon P, Deo M, Tuohey L, Whitehead C, Hannan NJ, Tong S. Kaitu'u-Lino TJ, et al. Among authors: hannan nj. Hypertension. 2017 Nov;70(5):1014-1024. doi: 10.1161/HYPERTENSIONAHA.117.09548. Epub 2017 Sep 25. Hypertension. 2017. PMID: 28947613
Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.
Thilakasiri P, Huynh J, Poh AR, Tan CW, Nero TL, Tran K, Parslow AC, Afshar-Sterle S, Baloyan D, Hannan NJ, Buchert M, Scott AM, Griffin MD, Hollande F, Parker MW, Putoczki TL, Ernst M, Chand AL. Thilakasiri P, et al. Among authors: hannan nj. EMBO Mol Med. 2019 Apr;11(4):e9539. doi: 10.15252/emmm.201809539. EMBO Mol Med. 2019. PMID: 30885958 Free PMC article.
Melatonin enhances antioxidant molecules in the placenta, reduces secretion of soluble fms-like tyrosine kinase 1 (sFLT) from primary trophoblast but does not rescue endothelial dysfunction: An evaluation of its potential to treat preeclampsia.
Hannan NJ, Binder NK, Beard S, Nguyen TV, Kaitu'u-Lino TJ, Tong S. Hannan NJ, et al. PLoS One. 2018 Apr 11;13(4):e0187082. doi: 10.1371/journal.pone.0187082. eCollection 2018. PLoS One. 2018. PMID: 29641523 Free PMC article.
148 results