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The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma.
Coulson R, Liew SH, Connelly AA, Yee NS, Deb S, Kumar B, Vargas AC, O'Toole SA, Parslow AC, Poh A, Putoczki T, Morrow RJ, Alorro M, Lazarus KA, Yeap EFW, Walton KL, Harrison CA, Hannan NJ, George AJ, Clyne CD, Ernst M, Allen AM, Chand AL. Coulson R, et al. Among authors: kumar b. Oncotarget. 2017 Mar 21;8(12):18640-18656. doi: 10.18632/oncotarget.15553. Oncotarget. 2017. PMID: 28416734 Free PMC article.
Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy.
Marini KD, Croucher DR, McCloy RA, Vaghjiani V, Gonzalez-Rajal A, Hastings JF, Chin V, Szczepny A, Kostyrko K, Marquez C, Jayasekara WSN, Alamgeer M, Boolell V, Han JZR, Waugh T, Lee HC, Oakes SR, Kumar B, Harrison CA, Hedger MP, Lorensuhewa N, Kita B, Barrow R, Robinson BW, de Kretser DM, Wu J, Ganju V, Sweet-Cordero EA, Burgess A, Martelotto LG, Rossello FJ, Cain JE, Watkins DN. Marini KD, et al. Among authors: kumar b. Sci Transl Med. 2018 Jul 25;10(451):eaat3504. doi: 10.1126/scitranslmed.aat3504. Sci Transl Med. 2018. PMID: 30045976
Tumor inherent interferon regulators as biomarkers of long-term chemotherapeutic response in TNBC.
Brockwell NK, Rautela J, Owen KL, Gearing LJ, Deb S, Harvey K, Spurling A, Zanker D, Chan CL, Cumming HE, Deng N, Zakhour JM, Duivenvoorden HM, Robinson T, Harris M, White M, Fox J, Ooi C, Kumar B, Thomson J, Potasz N, Swarbrick A, Hertzog PJ, Molloy TJ, Toole SO, Ganju V, Parker BS. Brockwell NK, et al. Among authors: kumar b. NPJ Precis Oncol. 2019 Aug 29;3:21. doi: 10.1038/s41698-019-0093-2. eCollection 2019. NPJ Precis Oncol. 2019. PMID: 31482136 Free PMC article.
STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis.
Dawson RE, Deswaerte V, West AC, Tang K, West AJ, Balic JJ, Gearing LJ, Saad MI, Yu L, Wu Y, Bhathal PS, Kumar B, Chakrabarti JT, Zavros Y, Oshima H, Klinman DM, Oshima M, Tan P, Jenkins BJ. Dawson RE, et al. Among authors: kumar b. Gut. 2022 Aug;71(8):1515-1531. doi: 10.1136/gutjnl-2020-323916. Epub 2021 Sep 6. Gut. 2022. PMID: 34489308
Evidence for cancer stem cells in human endometrial carcinoma.
Hubbard SA, Friel AM, Kumar B, Zhang L, Rueda BR, Gargett CE. Hubbard SA, et al. Among authors: kumar b. Cancer Res. 2009 Nov 1;69(21):8241-8. doi: 10.1158/0008-5472.CAN-08-4808. Epub 2009 Oct 20. Cancer Res. 2009. PMID: 19843861
In vivo evidence that RBM5 is a tumour suppressor in the lung.
Jamsai D, Watkins DN, O'Connor AE, Merriner DJ, Gursoy S, Bird AD, Kumar B, Miller A, Cole TJ, Jenkins BJ, O'Bryan MK. Jamsai D, et al. Among authors: kumar b. Sci Rep. 2017 Nov 24;7(1):16323. doi: 10.1038/s41598-017-15874-9. Sci Rep. 2017. PMID: 29176597 Free PMC article.
Blockade of the protease ADAM17 ameliorates experimental pancreatitis.
Saad MI, Weng T, Lundy J, Gearing LJ, West AC, Harpur CM, Alanazi M, Hodges C, Croagh D, Kumar B, Sagi I, Rose-John S, Jenkins BJ. Saad MI, et al. Among authors: kumar b. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2213744119. doi: 10.1073/pnas.2213744119. Epub 2022 Oct 10. Proc Natl Acad Sci U S A. 2022. PMID: 36215509 Free PMC article.
3,860 results