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Anti-LPS antibodies protect against Klebsiella pneumoniae by empowering neutrophil-mediated clearance without neutralizing TLR4.
Cohen TS, Pelletier M, Cheng L, Pennini ME, Bonnell J, Cvitkovic R, Chang CS, Xiao X, Cameroni E, Corti D, Semenova E, Warrener P, Sellman BR, Suzich J, Wang Q, Stover CK. Cohen TS, et al. Among authors: stover ck. JCI Insight. 2017 May 4;2(9):e92774. doi: 10.1172/jci.insight.92774. eCollection 2017 May 4. JCI Insight. 2017. PMID: 28469079 Free PMC article.
Target-Agnostic Identification of Functional Monoclonal Antibodies Against Klebsiella pneumoniae Multimeric MrkA Fimbrial Subunit.
Wang Q, Chang CS, Pennini M, Pelletier M, Rajan S, Zha J, Chen Y, Cvitkovic R, Sadowska A, Heidbrink Thompson J, Yu Lin H, Barnes A, Rickert K, Wilson S, Stover CK, Dall'Acqua WF, Chowdhury PS, Xiao X. Wang Q, et al. Among authors: stover ck. J Infect Dis. 2016 Jun 1;213(11):1800-8. doi: 10.1093/infdis/jiw021. Epub 2016 Jan 14. J Infect Dis. 2016. PMID: 26768253
Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections.
Cohen TS, Hilliard JJ, Jones-Nelson O, Keller AE, O'Day T, Tkaczyk C, DiGiandomenico A, Hamilton M, Pelletier M, Wang Q, Diep BA, Le VT, Cheng L, Suzich J, Stover CK, Sellman BR. Cohen TS, et al. Among authors: stover ck. Sci Transl Med. 2016 Mar 9;8(329):329ra31. doi: 10.1126/scitranslmed.aad9922. Sci Transl Med. 2016. PMID: 26962155
Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae.
Pennini ME, De Marco A, Pelletier M, Bonnell J, Cvitkovic R, Beltramello M, Cameroni E, Bianchi S, Zatta F, Zhao W, Xiao X, Camara MM, DiGiandomenico A, Semenova E, Lanzavecchia A, Warrener P, Suzich J, Wang Q, Corti D, Stover CK. Pennini ME, et al. Among authors: stover ck. Nat Commun. 2017 Dec 8;8(1):1991. doi: 10.1038/s41467-017-02223-7. Nat Commun. 2017. PMID: 29222409 Free PMC article.
Mouse model of Gram-negative prosthetic joint infection reveals therapeutic targets.
Thompson JM, Miller RJ, Ashbaugh AG, Dillen CA, Pickett JE, Wang Y, Ortines RV, Sterling RS, Francis KP, Bernthal NM, Cohen TS, Tkaczyk C, Yu L, Stover CK, DiGiandomenico A, Sellman BR, Thorek DL, Miller LS. Thompson JM, et al. Among authors: stover ck. JCI Insight. 2018 Sep 6;3(17):e121737. doi: 10.1172/jci.insight.121737. eCollection 2018 Sep 6. JCI Insight. 2018. PMID: 30185667 Free PMC article.
Antibacterial Monoclonal Antibodies Do Not Disrupt the Intestinal Microbiome or Its Function.
Jones-Nelson O, Tovchigrechko A, Glover MS, Fernandes F, Rangaswamy U, Liu H, Tabor DE, Boyd J, Warrener P, Martinez J, Hilliard JJ, Stover CK, Yu W, DAngelo G, Hess S, Cohen TS, Sellman BR. Jones-Nelson O, et al. Among authors: stover ck. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e02347-19. doi: 10.1128/AAC.02347-19. Print 2020 Apr 21. Antimicrob Agents Chemother. 2020. PMID: 32152087 Free PMC article.
101 results