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Targetable T-type Calcium Channels Drive Glioblastoma.
Zhang Y, Cruickshanks N, Yuan F, Wang B, Pahuski M, Wulfkuhle J, Gallagher I, Koeppel AF, Hatef S, Papanicolas C, Lee J, Bar EE, Schiff D, Turner SD, Petricoin EF, Gray LS, Abounader R. Zhang Y, et al. Cancer Res. 2017 Jul 1;77(13):3479-3490. doi: 10.1158/0008-5472.CAN-16-2347. Epub 2017 May 16. Cancer Res. 2017. PMID: 28512247 Free PMC article.
Hepatocyte growth factor sensitizes brain tumors to c-MET kinase inhibition.
Zhang Y, Farenholtz KE, Yang Y, Guessous F, Dipierro CG, Calvert VS, Deng J, Schiff D, Xin W, Lee JK, Purow B, Christensen J, Petricoin E, Abounader R. Zhang Y, et al. Clin Cancer Res. 2013 Mar 15;19(6):1433-44. doi: 10.1158/1078-0432.CCR-12-2832. Epub 2013 Feb 5. Clin Cancer Res. 2013. PMID: 23386689 Free PMC article.
Combined CDK4/6 and mTOR Inhibition Is Synergistic against Glioblastoma via Multiple Mechanisms.
Olmez I, Brenneman B, Xiao A, Serbulea V, Benamar M, Zhang Y, Manigat L, Abbas T, Lee J, Nakano I, Godlewski J, Bronisz A, Abounader R, Leitinger N, Purow B. Olmez I, et al. Among authors: zhang y. Clin Cancer Res. 2017 Nov 15;23(22):6958-6968. doi: 10.1158/1078-0432.CCR-17-0803. Epub 2017 Aug 16. Clin Cancer Res. 2017. PMID: 28814434 Free PMC article.
Discovery and Therapeutic Exploitation of Mechanisms of Resistance to MET Inhibitors in Glioblastoma.
Cruickshanks N, Zhang Y, Hine S, Gibert M, Yuan F, Oxford M, Grello C, Pahuski M, Dube C, Guessous F, Wang B, Deveau C, Saoud K, Gallagher I, Wulfkuhle J, Schiff D, Phan S, Petricoin E, Abounader R. Cruickshanks N, et al. Among authors: zhang y. Clin Cancer Res. 2019 Jan 15;25(2):663-673. doi: 10.1158/1078-0432.CCR-18-0926. Epub 2018 Sep 10. Clin Cancer Res. 2019. PMID: 30201763 Free PMC article.
MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes.
Li Y, Guessous F, Zhang Y, Dipierro C, Kefas B, Johnson E, Marcinkiewicz L, Jiang J, Yang Y, Schmittgen TD, Lopes B, Schiff D, Purow B, Abounader R. Li Y, et al. Among authors: zhang y. Cancer Res. 2009 Oct 1;69(19):7569-76. doi: 10.1158/0008-5472.CAN-09-0529. Epub 2009 Sep 22. Cancer Res. 2009. PMID: 19773441 Free PMC article.
microRNA-34a is tumor suppressive in brain tumors and glioma stem cells.
Guessous F, Zhang Y, Kofman A, Catania A, Li Y, Schiff D, Purow B, Abounader R. Guessous F, et al. Among authors: zhang y. Cell Cycle. 2010 Mar 15;9(6):1031-6. doi: 10.4161/cc.9.6.10987. Epub 2010 Mar 15. Cell Cycle. 2010. PMID: 20190569 Free PMC article.
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