Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

46 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia.
Tharkar-Promod S, Johnson DP, Bennett SE, Dennis EM, Banowsky BG, Jones SS, Shearstone JR, Quayle SN, Min C, Jarpe M, Mosbruger T, Pomicter AD, Miles RR, Chen WY, Bhalla KN, Zweidler-McKay PA, Shrieve DC, Deininger MW, Chandrasekharan MB, Bhaskara S. Tharkar-Promod S, et al. Among authors: chandrasekharan mb. Leukemia. 2018 Jan;32(1):49-60. doi: 10.1038/leu.2017.174. Epub 2017 Jun 5. Leukemia. 2018. PMID: 28579617 Free PMC article.
HDAC1,2 inhibition impairs EZH2- and BBAP-mediated DNA repair to overcome chemoresistance in EZH2 gain-of-function mutant diffuse large B-cell lymphoma.
Johnson DP, Spitz GS, Tharkar S, Quayle SN, Shearstone JR, Jones S, McDowell ME, Wellman H, Tyler JK, Cairns BR, Chandrasekharan MB, Bhaskara S. Johnson DP, et al. Among authors: chandrasekharan mb. Oncotarget. 2015 Mar 10;6(7):4863-87. doi: 10.18632/oncotarget.3120. Oncotarget. 2015. PMID: 25605023 Free PMC article.
Interaction of the Jhd2 Histone H3 Lys-4 Demethylase with Chromatin Is Controlled by Histone H2A Surfaces and Restricted by H2B Ubiquitination.
Huang F, Ramakrishnan S, Pokhrel S, Pflueger C, Parnell TJ, Kasten MM, Currie SL, Bhachech N, Horikoshi M, Graves BJ, Cairns BR, Bhaskara S, Chandrasekharan MB. Huang F, et al. Among authors: chandrasekharan mb. J Biol Chem. 2015 Nov 27;290(48):28760-77. doi: 10.1074/jbc.M115.693085. Epub 2015 Oct 8. J Biol Chem. 2015. PMID: 26451043 Free PMC article.
Targeting DNA Repair and Chromatin Crosstalk in Cancer Therapy.
Johnson DP, Chandrasekharan MB, Dutreix M, Bhaskara S. Johnson DP, et al. Among authors: chandrasekharan mb. Cancers (Basel). 2021 Jan 20;13(3):381. doi: 10.3390/cancers13030381. Cancers (Basel). 2021. PMID: 33498525 Free PMC article. Review.
A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation.
Hess L, Moos V, Lauber AA, Reiter W, Schuster M, Hartl N, Lackner D, Boenke T, Koren A, Guzzardo PM, Gundacker B, Riegler A, Vician P, Miccolo C, Leiter S, Chandrasekharan MB, Vcelkova T, Tanzer A, Jun JQ, Bradner J, Brosch G, Hartl M, Bock C, Bürckstümmer T, Kubicek S, Chiocca S, Bhaskara S, Seiser C. Hess L, et al. Among authors: chandrasekharan mb. PLoS Genet. 2022 Aug 22;18(8):e1010376. doi: 10.1371/journal.pgen.1010376. eCollection 2022 Aug. PLoS Genet. 2022. PMID: 35994477 Free PMC article.
46 results