Baker D - Search Results

1

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.

Strauch EM, Bernard SM, La D, Bohn AJ, Lee PS, Anderson CE, Nieusma T, Holstein CA, Garcia NK, Hooper KA, Ravichandran R, Nelson JW, Sheffler W, Bloom JD, Lee KK, Ward AB, Yager P, Fuller DH, Wilson IA, Baker D. Strauch EM, et al. Among authors: baker d. Nat Biotechnol. 2017 Jul;35(7):667-671. doi: 10.1038/nbt.3907. Epub 2017 Jun 12. Nat Biotechnol. 2017. PMID: 28604661 Free PMC article.

2

A surprising simplicity to protein folding.

Baker D. Baker D. Nature. 2000 May 4;405(6782):39-42. doi: 10.1038/35011000. Nature. 2000. PMID: 10811210

3

Computational redesign of protein-protein interaction specificity.

Kortemme T, Joachimiak LA, Bullock AN, Schuler AD, Stoddard BL, Baker D. Kortemme T, et al. Among authors: baker d. Nat Struct Mol Biol. 2004 Apr;11(4):371-9. doi: 10.1038/nsmb749. Epub 2004 Mar 21. Nat Struct Mol Biol. 2004. PMID: 15034550

4

Computational redesign of endonuclease DNA binding and cleavage specificity.

Ashworth J, Havranek JJ, Duarte CM, Sussman D, Monnat RJ Jr, Stoddard BL, Baker D. Ashworth J, et al. Among authors: baker d. Nature. 2006 Jun 1;441(7093):656-9. doi: 10.1038/nature04818. Nature. 2006. PMID: 16738662 Free PMC article.

5

Structure prediction for CASP7 targets using extensive all-atom refinement with Rosetta@home.

Das R, Qian B, Raman S, Vernon R, Thompson J, Bradley P, Khare S, Tyka MD, Bhat D, Chivian D, Kim DE, Sheffler WH, Malmström L, Wollacott AM, Wang C, Andre I, Baker D. Das R, et al. Among authors: baker d. Proteins. 2007;69 Suppl 8:118-28. doi: 10.1002/prot.21636. Proteins. 2007. PMID: 17894356

6

High-resolution structure prediction and the crystallographic phase problem.

Qian B, Raman S, Das R, Bradley P, McCoy AJ, Read RJ, Baker D. Qian B, et al. Among authors: baker d. Nature. 2007 Nov 8;450(7167):259-64. doi: 10.1038/nature06249. Epub 2007 Oct 14. Nature. 2007. PMID: 17934447 Free PMC article.

7

Kemp elimination catalysts by computational enzyme design.

Röthlisberger D, Khersonsky O, Wollacott AM, Jiang L, DeChancie J, Betker J, Gallaher JL, Althoff EA, Zanghellini A, Dym O, Albeck S, Houk KN, Tawfik DS, Baker D. Röthlisberger D, et al. Among authors: baker d. Nature. 2008 May 8;453(7192):190-5. doi: 10.1038/nature06879. Epub 2008 Mar 19. Nature. 2008. PMID: 18354394

8

Exploitation of binding energy for catalysis and design.

Thyme SB, Jarjour J, Takeuchi R, Havranek JJ, Ashworth J, Scharenberg AM, Stoddard BL, Baker D. Thyme SB, et al. Among authors: baker d. Nature. 2009 Oct 29;461(7268):1300-4. doi: 10.1038/nature08508. Nature. 2009. PMID: 19865174 Free PMC article.

9

RosettaHoles2: a volumetric packing measure for protein structure refinement and validation.

Sheffler W, Baker D. Sheffler W, et al. Among authors: baker d. Protein Sci. 2010 Oct;19(10):1991-5. doi: 10.1002/pro.458. Protein Sci. 2010. PMID: 20665689 Free PMC article.

10

Computational design of proteins targeting the conserved stem region of influenza hemagglutinin.

Fleishman SJ, Whitehead TA, Ekiert DC, Dreyfus C, Corn JE, Strauch EM, Wilson IA, Baker D. Fleishman SJ, et al. Among authors: baker d. Science. 2011 May 13;332(6031):816-21. doi: 10.1126/science.1202617. Science. 2011. PMID: 21566186 Free PMC article.

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