Lee PS - Search Results

1

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.

Strauch EM, Bernard SM, La D, Bohn AJ, Lee PS, Anderson CE, Nieusma T, Holstein CA, Garcia NK, Hooper KA, Ravichandran R, Nelson JW, Sheffler W, Bloom JD, Lee KK, Ward AB, Yager P, Fuller DH, Wilson IA, Baker D. Strauch EM, et al. Among authors: lee kk, lee ps. Nat Biotechnol. 2017 Jul;35(7):667-671. doi: 10.1038/nbt.3907. Epub 2017 Jun 12. Nat Biotechnol. 2017. PMID: 28604661 Free PMC article.

2

Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site.

Hong M, Lee PS, Hoffman RM, Zhu X, Krause JC, Laursen NS, Yoon SI, Song L, Tussey L, Crowe JE Jr, Ward AB, Wilson IA. Hong M, et al. Among authors: lee ps. J Virol. 2013 Nov;87(22):12471-80. doi: 10.1128/JVI.01388-13. Epub 2013 Sep 11. J Virol. 2013. PMID: 24027321 Free PMC article.

3

Structural characterization of viral epitopes recognized by broadly cross-reactive antibodies.

Lee PS, Wilson IA. Lee PS, et al. Curr Top Microbiol Immunol. 2015;386:323-41. doi: 10.1007/82_2014_413. Curr Top Microbiol Immunol. 2015. PMID: 25037260 Free PMC article. Review.

4

Design and Structure of an Engineered Disulfide-Stabilized Influenza Virus Hemagglutinin Trimer.

Lee PS, Zhu X, Yu W, Wilson IA. Lee PS, et al. J Virol. 2015 Jul;89(14):7417-20. doi: 10.1128/JVI.00808-15. Epub 2015 Apr 29. J Virol. 2015. PMID: 25926650 Free PMC article.

5

A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response.

Koday MT, Nelson J, Chevalier A, Koday M, Kalinoski H, Stewart L, Carter L, Nieusma T, Lee PS, Ward AB, Wilson IA, Dagley A, Smee DF, Baker D, Fuller DH. Koday MT, et al. Among authors: lee ps. PLoS Pathog. 2016 Feb 4;12(2):e1005409. doi: 10.1371/journal.ppat.1005409. eCollection 2016 Feb. PLoS Pathog. 2016. PMID: 26845438 Free PMC article.

6

Heterosubtypic antibody recognition of the influenza virus hemagglutinin receptor binding site enhanced by avidity.

Lee PS, Yoshida R, Ekiert DC, Sakai N, Suzuki Y, Takada A, Wilson IA. Lee PS, et al. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17040-5. doi: 10.1073/pnas.1212371109. Epub 2012 Oct 1. Proc Natl Acad Sci U S A. 2012. PMID: 23027945 Free PMC article.

7

Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA.

Julien JP, Lee PS, Wilson IA. Julien JP, et al. Among authors: lee ps. Immunol Rev. 2012 Nov;250(1):180-98. doi: 10.1111/imr.12005. Immunol Rev. 2012. PMID: 23046130 Free PMC article. Review.

8

Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.

Lee PS, Ohshima N, Stanfield RL, Yu W, Iba Y, Okuno Y, Kurosawa Y, Wilson IA. Lee PS, et al. Nat Commun. 2014 Apr 10;5:3614. doi: 10.1038/ncomms4614. Nat Commun. 2014. PMID: 24717798 Free PMC article.

9

Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin.

Tan GS, Lee PS, Hoffman RM, Mazel-Sanchez B, Krammer F, Leon PE, Ward AB, Wilson IA, Palese P. Tan GS, et al. Among authors: lee ps. J Virol. 2014 Dec;88(23):13580-92. doi: 10.1128/JVI.02289-14. Epub 2014 Sep 10. J Virol. 2014. PMID: 25210195 Free PMC article.

10

Structure of the apo anti-influenza CH65 Fab.

Lee PS, Arnell AJ, Wilson IA. Lee PS, et al. Acta Crystallogr F Struct Biol Commun. 2015 Feb;71(Pt 2):145-8. doi: 10.1107/S2053230X14027599. Epub 2015 Jan 28. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25664786 Free PMC article.

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