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Recognition of lyso-phospholipids by human natural killer T lymphocytes.
Fox LM, Cox DG, Lockridge JL, Wang X, Chen X, Scharf L, Trott DL, Ndonye RM, Veerapen N, Besra GS, Howell AR, Cook ME, Adams EJ, Hildebrand WH, Gumperz JE. Fox LM, et al. Among authors: adams ej. PLoS Biol. 2009 Oct;7(10):e1000228. doi: 10.1371/journal.pbio.1000228. Epub 2009 Oct 27. PLoS Biol. 2009. PMID: 19859526 Free PMC article.
The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation.
Scharf L, Li NS, Hawk AJ, Garzón D, Zhang T, Fox LM, Kazen AR, Shah S, Haddadian EJ, Gumperz JE, Saghatelian A, Faraldo-Gómez JD, Meredith SC, Piccirilli JA, Adams EJ. Scharf L, et al. Among authors: adams ej. Immunity. 2010 Dec 14;33(6):853-62. doi: 10.1016/j.immuni.2010.11.026. Immunity. 2010. PMID: 21167756 Free PMC article.
Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires.
Gleimer M, Wahl AR, Hickman HD, Abi-Rached L, Norman PJ, Guethlein LA, Hammond JA, Draghi M, Adams EJ, Juo S, Jalili R, Gharizadeh B, Ronaghi M, Garcia KC, Hildebrand WH, Parham P. Gleimer M, et al. Among authors: adams ej. J Immunol. 2011 Feb 1;186(3):1575-88. doi: 10.4049/jimmunol.1002990. Epub 2011 Jan 5. J Immunol. 2011. PMID: 21209280 Free PMC article.
The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins.
López-Sagaseta J, Dulberger CL, Crooks JE, Parks CD, Luoma AM, McFedries A, Van Rhijn I, Saghatelian A, Adams EJ. López-Sagaseta J, et al. Among authors: adams ej. Proc Natl Acad Sci U S A. 2013 May 7;110(19):E1771-8. doi: 10.1073/pnas.1222678110. Epub 2013 Apr 23. Proc Natl Acad Sci U S A. 2013. PMID: 23613577 Free PMC article.
270 results