Yuan S - Search Results

1

Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo.

Yuan S, Chan JF, den-Haan H, Chik KK, Zhang AJ, Chan CC, Poon VK, Yip CC, Mak WW, Zhu Z, Zou Z, Tee KM, Cai JP, Chan KH, de la Peña J, Pérez-Sánchez H, Cerón-Carrasco JP, Yuen KY. Yuan S, et al. Antiviral Res. 2017 Sep;145:33-43. doi: 10.1016/j.antiviral.2017.07.007. Epub 2017 Jul 14. Antiviral Res. 2017. PMID: 28712942

2

Comparative immunological evaluation of recombinant Salmonella Typhimurium strains expressing model antigens as live oral vaccines.

Zheng SY, Yu B, Zhang K, Chen M, Hua YH, Yuan S, Watt RM, Zheng BJ, Yuen KY, Huang JD. Zheng SY, et al. Among authors: yuan s. BMC Immunol. 2012 Sep 26;13:54. doi: 10.1186/1471-2172-13-54. BMC Immunol. 2012. PMID: 23013063 Free PMC article.

3

Identification of a small-molecule inhibitor of influenza virus via disrupting the subunits interaction of the viral polymerase.

Yuan S, Chu H, Zhao H, Zhang K, Singh K, Chow BK, Kao RY, Zhou J, Zheng BJ. Yuan S, et al. Antiviral Res. 2016 Jan;125:34-42. doi: 10.1016/j.antiviral.2015.11.005. Epub 2015 Nov 22. Antiviral Res. 2016. PMID: 26593979

4

A novel small-molecule inhibitor of influenza A virus acts by suppressing PA endonuclease activity of the viral polymerase.

Yuan S, Chu H, Singh K, Zhao H, Zhang K, Kao RY, Chow BK, Zhou J, Zheng BJ. Yuan S, et al. Sci Rep. 2016 Mar 9;6:22880. doi: 10.1038/srep22880. Sci Rep. 2016. PMID: 26956222 Free PMC article.

5

Novel residues in the PA protein of avian influenza H7N7 virus affect virulence in mammalian hosts.

Zhao H, Chu H, Zhao X, Shuai H, Wong BH, Wen L, Yuan S, Zheng BJ, Zhou J, Yuen KY. Zhao H, et al. Among authors: yuan s. Virology. 2016 Nov;498:1-8. doi: 10.1016/j.virol.2016.08.004. Epub 2016 Aug 12. Virology. 2016. PMID: 27525812 Free article.

6

Identification of a novel small-molecule compound targeting the influenza A virus polymerase PB1-PB2 interface.

Yuan S, Chu H, Ye J, Singh K, Ye Z, Zhao H, Kao RY, Chow BK, Zhou J, Zheng BJ. Yuan S, et al. Antiviral Res. 2017 Jan;137:58-66. doi: 10.1016/j.antiviral.2016.11.005. Epub 2016 Nov 10. Antiviral Res. 2017. PMID: 27840201 Free PMC article.

7

Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitor.

Chan JF, Chik KK, Yuan S, Yip CC, Zhu Z, Tee KM, Tsang JO, Chan CC, Poon VK, Lu G, Zhang AJ, Lai KK, Chan KH, Kao RY, Yuen KY. Chan JF, et al. Among authors: yuan s. Antiviral Res. 2017 May;141:29-37. doi: 10.1016/j.antiviral.2017.02.002. Epub 2017 Feb 7. Antiviral Res. 2017. PMID: 28185815

8

Antibody-Dependent Cell-Mediated Cytotoxicity Epitopes on the Hemagglutinin Head Region of Pandemic H1N1 Influenza Virus Play Detrimental Roles in H1N1-Infected Mice.

Ye ZW, Yuan S, Poon KM, Wen L, Yang D, Sun Z, Li C, Hu M, Shuai H, Zhou J, Zhang MY, Zheng BJ, Chu H, Yuen KY. Ye ZW, et al. Among authors: yuan s. Front Immunol. 2017 Mar 21;8:317. doi: 10.3389/fimmu.2017.00317. eCollection 2017. Front Immunol. 2017. PMID: 28377769 Free PMC article.

9

Inhibitors of Influenza A Virus Polymerase.

Yuan S, Wen L, Zhou J. Yuan S, et al. ACS Infect Dis. 2018 Mar 9;4(3):218-223. doi: 10.1021/acsinfecdis.7b00265. Epub 2018 Jan 22. ACS Infect Dis. 2018. PMID: 29355011 Review.

10

Large-scale sequence analysis reveals novel human-adaptive markers in PB2 segment of seasonal influenza A viruses.

Wen L, Chu H, Wong BH, Wang D, Li C, Zhao X, Chiu MC, Yuan S, Fan Y, Chen H, Zhou J, Yuen KY. Wen L, et al. Among authors: yuan s. Emerg Microbes Infect. 2018 Mar 29;7(1):47. doi: 10.1038/s41426-018-0050-0. Emerg Microbes Infect. 2018. PMID: 29593225 Free PMC article.

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