Hawley SA - Search Results

1

Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK.

Zhang CS, Hawley SA, Zong Y, Li M, Wang Z, Gray A, Ma T, Cui J, Feng JW, Zhu M, Wu YQ, Li TY, Ye Z, Lin SY, Yin H, Piao HL, Hardie DG, Lin SC. Zhang CS, et al. Among authors: hawley sa. Nature. 2017 Aug 3;548(7665):112-116. doi: 10.1038/nature23275. Epub 2017 Jul 19. Nature. 2017. PMID: 28723898 Free PMC article.

2

AMPK: a nutrient and energy sensor that maintains energy homeostasis.

Hardie DG, Ross FA, Hawley SA. Hardie DG, et al. Among authors: hawley sa. Nat Rev Mol Cell Biol. 2012 Mar 22;13(4):251-62. doi: 10.1038/nrm3311. Nat Rev Mol Cell Biol. 2012. PMID: 22436748 Free PMC article. Review.

3

Cell-Free Assays to Measure Effects of Regulatory Ligands on AMPK.

Fyffe FA, Hawley SA, Gray A, Hardie DG. Fyffe FA, et al. Among authors: hawley sa. Methods Mol Biol. 2018;1732:69-86. doi: 10.1007/978-1-4939-7598-3_5. Methods Mol Biol. 2018. PMID: 29480469

4

Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress.

Zong Y, Zhang CS, Li M, Wang W, Wang Z, Hawley SA, Ma T, Feng JW, Tian X, Qi Q, Wu YQ, Zhang C, Ye Z, Lin SY, Piao HL, Hardie DG, Lin SC. Zong Y, et al. Among authors: hawley sa. Cell Res. 2019 Jun;29(6):460-473. doi: 10.1038/s41422-019-0163-6. Epub 2019 Apr 4. Cell Res. 2019. PMID: 30948787 Free PMC article.

5

Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1.

Li M, Zhang CS, Feng JW, Wei X, Zhang C, Xie C, Wu Y, Hawley SA, Atrih A, Lamont DJ, Wang Z, Piao HL, Hardie DG, Lin SC. Li M, et al. Among authors: hawley sa. Cell Res. 2021 Apr;31(4):478-481. doi: 10.1038/s41422-020-00456-8. Epub 2020 Dec 21. Cell Res. 2021. PMID: 33349646 Free PMC article. No abstract available.

6

The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism.

Hawley SA, Gadalla AE, Olsen GS, Hardie DG. Hawley SA, et al. Diabetes. 2002 Aug;51(8):2420-5. doi: 10.2337/diabetes.51.8.2420. Diabetes. 2002. PMID: 12145153

7

AMP-activated protein kinase--development of the energy sensor concept.

Hardie DG, Hawley SA, Scott JW. Hardie DG, et al. Among authors: hawley sa. J Physiol. 2006 Jul 1;574(Pt 1):7-15. doi: 10.1113/jphysiol.2006.108944. Epub 2006 Apr 27. J Physiol. 2006. PMID: 16644800 Free PMC article. Review.

8

Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP.

Fogarty S, Hawley SA, Green KA, Saner N, Mustard KJ, Hardie DG. Fogarty S, et al. Among authors: hawley sa. Biochem J. 2010 Jan 27;426(1):109-18. doi: 10.1042/BJ20091372. Biochem J. 2010. PMID: 19958286 Free PMC article.

9

Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation.

Hawley SA, Ross FA, Chevtzoff C, Green KA, Evans A, Fogarty S, Towler MC, Brown LJ, Ogunbayo OA, Evans AM, Hardie DG. Hawley SA, et al. Cell Metab. 2010 Jun 9;11(6):554-65. doi: 10.1016/j.cmet.2010.04.001. Cell Metab. 2010. PMID: 20519126 Free PMC article.

10

AMP-activated protein kinase: a target for drugs both ancient and modern.

Hardie DG, Ross FA, Hawley SA. Hardie DG, et al. Among authors: hawley sa. Chem Biol. 2012 Oct 26;19(10):1222-36. doi: 10.1016/j.chembiol.2012.08.019. Chem Biol. 2012. PMID: 23102217 Free PMC article. Review.

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