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Thiopurines Dosed to a Therapeutic 6-Thioguanine Level in Combination with Adalimumab Are More Effective Than Subtherapeutic Thiopurine-based Combination Therapy or Adalimumab Monotherapy During Induction and Maintenance in Patients with Long-standing Crohn's Disease.
Kariyawasam VC, Ward MG, Blaker PA, Patel KV, Goel R, Sanderson JD, Irving PM. Kariyawasam VC, et al. Among authors: blaker pa. Inflamm Bowel Dis. 2017 Sep;23(9):1555-1565. doi: 10.1097/MIB.0000000000001183. Inflamm Bowel Dis. 2017. PMID: 28786865
Thioguanine in inflammatory bowel disease: Long-term efficacy and safety.
Ward MG, Patel KV, Kariyawasam VC, Goel R, Warner B, Elliott TR, Blaker PA, Irving PM, Marinaki AM, Sanderson JD. Ward MG, et al. Among authors: blaker pa. United European Gastroenterol J. 2017 Jun;5(4):563-570. doi: 10.1177/2050640616663438. Epub 2016 Aug 1. United European Gastroenterol J. 2017. PMID: 28588888 Free PMC article.
Is there a role for thioguanine therapy in IBD in 2017 and beyond?
Taylor KM, Ward MG, Blaker PA, Sparrow MP. Taylor KM, et al. Among authors: blaker pa. Expert Rev Gastroenterol Hepatol. 2017 May;11(5):473-486. doi: 10.1080/17474124.2017.1294062. Epub 2017 Feb 20. Expert Rev Gastroenterol Hepatol. 2017. PMID: 28276819 Review.
A practical guide to the use of thiopurines in oral medicine.
Hullah EA, Blaker PA, Marinaki AM, Escudier MP, Sanderson JD. Hullah EA, et al. Among authors: blaker pa. J Oral Pathol Med. 2015 Nov;44(10):761-8. doi: 10.1111/jop.12274. Epub 2014 Dec 19. J Oral Pathol Med. 2015. PMID: 25529219 Review.
Optimizing the use of thiopurines in inflammatory bowel disease.
Goel RM, Blaker P, Mentzer A, Fong SC, Marinaki AM, Sanderson JD. Goel RM, et al. Ther Adv Chronic Dis. 2015 May;6(3):138-46. doi: 10.1177/2040622315579063. Ther Adv Chronic Dis. 2015. PMID: 25954498 Free PMC article. Review.
Mechanism of allopurinol induced TPMT inhibition.
Blaker PA, Arenas-Hernandez M, Smith MA, Shobowale-Bakre EA, Fairbanks L, Irving PM, Sanderson JD, Marinaki AM. Blaker PA, et al. Biochem Pharmacol. 2013 Aug 15;86(4):539-47. doi: 10.1016/j.bcp.2013.06.002. Epub 2013 Jun 14. Biochem Pharmacol. 2013. PMID: 23770457
20 results