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The new-generation pan-peroxisome proliferator-activated receptor agonist IVA337 protects the liver from metabolic disorders and fibrosis.
Wettstein G, Luccarini JM, Poekes L, Faye P, Kupkowski F, Adarbes V, Defrêne E, Estivalet C, Gawronski X, Jantzen I, Philippot A, Tessier J, Tuyaa-Boustugue P, Oakley F, Mann DA, Leclercq I, Francque S, Konstantinova I, Broqua P, Junien JL. Wettstein G, et al. Among authors: konstantinova i. Hepatol Commun. 2017 Jun 19;1(6):524-537. doi: 10.1002/hep4.1057. eCollection 2017 Aug. Hepatol Commun. 2017. PMID: 29404476 Free PMC article.
The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis.
Derrett-Smith E, Clark KEN, Shiwen X, Abraham DJ, Hoyles RK, Lacombe O, Broqua P, Junien JL, Konstantinova I, Ong VH, Denton CP. Derrett-Smith E, et al. Among authors: konstantinova i. Arthritis Res Ther. 2021 Sep 6;23(1):234. doi: 10.1186/s13075-021-02592-x. Arthritis Res Ther. 2021. PMID: 34488870 Free PMC article.
Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression.
Ciuclan L, Hussey MJ, Burton V, Good R, Duggan N, Beach S, Jones P, Fox R, Clay I, Bonneau O, Konstantinova I, Pearce A, Rowlands DJ, Jarai G, Westwick J, MacLean MR, Thomas M. Ciuclan L, et al. Among authors: konstantinova i. Am J Respir Crit Care Med. 2013 Jan 1;187(1):78-89. doi: 10.1164/rccm.201206-1028OC. Epub 2012 Oct 18. Am J Respir Crit Care Med. 2013. PMID: 23087024
Optimization of Platelet-Derived Growth Factor Receptor (PDGFR) Inhibitors for Duration of Action, as an Inhaled Therapy for Lung Remodeling in Pulmonary Arterial Hypertension.
Shaw DE, Baig F, Bruce I, Chamoin S, Collingwood SP, Cross S, Dayal S, Drückes P, Furet P, Furminger V, Haggart D, Hussey M, Konstantinova I, Loren JC, Molteni V, Roberts S, Reilly J, Saunders AM, Stringer R, Sviridenko L, Thomas M, Thomson CG, Tomlins C, Wen B, Yeh V, Pearce AC. Shaw DE, et al. Among authors: konstantinova i. J Med Chem. 2016 Sep 8;59(17):7901-14. doi: 10.1021/acs.jmedchem.6b00703. Epub 2016 Aug 19. J Med Chem. 2016. PMID: 27502700
New Biocides Based on N4-Alkylcytidines: Effects on Microorganisms and Application for the Protection of Cultural Heritage Objects of Painting.
Alexandrova LA, Oskolsky IA, Makarov DA, Jasko MV, Karpenko IL, Efremenkova OV, Vasilyeva BF, Avdanina DA, Ermolyuk AA, Benko EE, Kalinin SG, Kolganova TV, Berzina MY, Konstantinova ID, Chizhov AO, Kochetkov SN, Zhgun AA. Alexandrova LA, et al. Among authors: konstantinova id. Int J Mol Sci. 2024 Mar 6;25(5):3053. doi: 10.3390/ijms25053053. Int J Mol Sci. 2024. PMID: 38474298 Free PMC article.
New Flexible Analogues of 8-Aza-7-deazapurine Nucleosides as Potential Antibacterial Agents.
Khandazhinskaya A, Eletskaya B, Mironov A, Konstantinova I, Efremenkova O, Andreevskaya S, Smirnova T, Chernousova L, Kondrashova E, Chizhov A, Seley-Radtke K, Kochetkov S, Matyugina E. Khandazhinskaya A, et al. Among authors: konstantinova i. Int J Mol Sci. 2023 Oct 21;24(20):15421. doi: 10.3390/ijms242015421. Int J Mol Sci. 2023. PMID: 37895100 Free PMC article.
Intramolecular Hydrogen Bonding in N6-Substituted 2-Chloroadenosines: Evidence from NMR Spectroscopy.
Berzina MY, Eletskaya BZ, Kayushin AL, Dorofeeva EV, Lutonina OI, Fateev IV, Zhavoronkova ON, Bashorin AR, Arnautova AO, Smirnova OS, Antonov KV, Paramonov AS, Dubinnyi MA, Esipov RS, Miroshnikov AI, Konstantinova ID. Berzina MY, et al. Among authors: konstantinova id. Int J Mol Sci. 2023 Jun 2;24(11):9697. doi: 10.3390/ijms24119697. Int J Mol Sci. 2023. PMID: 37298648 Free PMC article.
Enzymatic Synthesis of 2-Chloropurine Arabinonucleosides with Chiral Amino Acid Amides at the C6 Position and an Evaluation of Antiproliferative Activity In Vitro.
Eletskaya BZ, Berzina MY, Fateev IV, Kayushin AL, Dorofeeva EV, Lutonina OI, Zorina EA, Antonov KV, Paramonov AS, Muzyka IS, Zhukova OS, Kiselevskiy MV, Miroshnikov AI, Esipov RS, Konstantinova ID. Eletskaya BZ, et al. Among authors: konstantinova id. Int J Mol Sci. 2023 Mar 25;24(7):6223. doi: 10.3390/ijms24076223. Int J Mol Sci. 2023. PMID: 37047197 Free PMC article.
184 results