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15 results

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Page 1
A dose-escalation study of bi-daily once weekly oral docetaxel either as ModraDoc001 or ModraDoc006 combined with ritonavir.
de Weger VA, Stuurman FE, Hendrikx JJMA, Moes JJ, Sawicki E, Huitema ADR, Nuijen B, Thijssen B, Rosing H, Keessen M, Mergui-Roelvink M, Beijnen JH, Schellens JHM, Marchetti S. de Weger VA, et al. Among authors: keessen m. Eur J Cancer. 2017 Nov;86:217-225. doi: 10.1016/j.ejca.2017.09.010. Epub 2017 Oct 12. Eur J Cancer. 2017. PMID: 29031170 Clinical Trial.
Phase I pharmacokinetic study of the safety and tolerability of lapatinib (GW572016) in combination with oxaliplatin/fluorouracil/leucovorin (FOLFOX4) in patients with solid tumors.
Siegel-Lakhai WS, Beijnen JH, Vervenne WL, Boot H, Keessen M, Versola M, Koch KM, Smith DA, Pandite L, Richel DJ, Schellens JH. Siegel-Lakhai WS, et al. Among authors: keessen m. Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4495-502. doi: 10.1158/1078-0432.CCR-07-0004. Clin Cancer Res. 2007. PMID: 17671135 Clinical Trial.
The effect of Echinacea purpurea on the pharmacokinetics of docetaxel.
Goey AK, Meijerman I, Rosing H, Burgers JA, Mergui-Roelvink M, Keessen M, Marchetti S, Beijnen JH, Schellens JH. Goey AK, et al. Among authors: keessen m. Br J Clin Pharmacol. 2013 Sep;76(3):467-74. doi: 10.1111/bcp.12159. Br J Clin Pharmacol. 2013. PMID: 23701184 Free PMC article. Clinical Trial.
The effect of St John's wort on the pharmacokinetics of docetaxel.
Goey AK, Meijerman I, Rosing H, Marchetti S, Mergui-Roelvink M, Keessen M, Burgers JA, Beijnen JH, Schellens JH. Goey AK, et al. Among authors: keessen m. Clin Pharmacokinet. 2014 Jan;53(1):103-10. doi: 10.1007/s40262-013-0102-5. Clin Pharmacokinet. 2014. PMID: 24068654 Clinical Trial.
Phase I and pharmacological trial of lapatinib in combination with gemcitabine in patients with advanced breast cancer.
van der Noll R, Smit WM, Wymenga AN, Boss DS, Grob M, Huitema AD, Rosing H, Tibben MM, Keessen M, Rehorst H, Beijnen JH, Schellens JH. van der Noll R, et al. Among authors: keessen m. Invest New Drugs. 2015 Dec;33(6):1197-205. doi: 10.1007/s10637-015-0281-z. Epub 2015 Sep 11. Invest New Drugs. 2015. PMID: 26362459 Free PMC article. Clinical Trial.
A Phase I Dose Escalation Study of Once-Weekly Oral Administration of Docetaxel as ModraDoc001 Capsule or ModraDoc006 Tablet in Combination with Ritonavir.
de Weger VA, Stuurman FE, Koolen SLW, Moes JJ, Hendrikx JJMA, Sawicki E, Thijssen B, Keessen M, Rosing H, Mergui-Roelvink M, Huitema ADR, Nuijen B, Beijnen JH, Schellens JHM, Marchetti S. de Weger VA, et al. Among authors: keessen m. Clin Cancer Res. 2019 Sep 15;25(18):5466-5474. doi: 10.1158/1078-0432.CCR-17-2299. Epub 2019 Jun 19. Clin Cancer Res. 2019. PMID: 31217201 Clinical Trial.
Effect of Food on the Pharmacokinetics of the Oral Docetaxel Tablet Formulation ModraDoc006 Combined with Ritonavir (ModraDoc006/r) in Patients with Advanced Solid Tumours.
Vermunt MAC, de Weger VA, Janssen JM, Lopez-Yurda MI, Keessen M, Thijssen B, Rosing H, Huitema ADR, Beijnen JH, Marchetti S. Vermunt MAC, et al. Among authors: keessen m. Drugs R D. 2021 Mar;21(1):103-111. doi: 10.1007/s40268-020-00336-x. Epub 2021 Jan 19. Drugs R D. 2021. PMID: 33464545 Free PMC article. Clinical Trial.
ModraDoc006, an oral docetaxel formulation in combination with ritonavir (ModraDoc006/r), in metastatic castration-resistant prostate cancer patients: A phase Ib study.
Vermunt MAC, Robbrecht DGJ, Devriese LA, Janssen JM, Thijssen B, Keessen M, van Eijk M, Kessels R, Eskens FALM, Beijnen JH, Mehra N, Bergman AM. Vermunt MAC, et al. Among authors: keessen m. Cancer Rep (Hoboken). 2021 Aug;4(4):e1367. doi: 10.1002/cnr2.1367. Epub 2021 Mar 12. Cancer Rep (Hoboken). 2021. PMID: 33709626 Free PMC article. Clinical Trial.
A global phase II randomized trial comparing oral taxane ModraDoc006/r to intravenous docetaxel in metastatic castration resistant prostate cancer.
Vaishampayan UN, Keessen M, Dreicer R, Heath EI, Buchler T, Árkosy PF, Csöszi T, Wiechno P, Kopyltsov E, Orlov SV, Plekhanov A, Smagina M, Varlamov S, Shore ND. Vaishampayan UN, et al. Among authors: keessen m. Eur J Cancer. 2024 May;202:114007. doi: 10.1016/j.ejca.2024.114007. Epub 2024 Mar 11. Eur J Cancer. 2024. PMID: 38518534 Clinical Trial.
15 results