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Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation.
Strawbridge RJ, Silveira A, Hoed MD, Gustafsson S, Luan J, Rybin D, Dupuis J, Li-Gao R, Kavousi M, Dehghan A, Haljas K, Lahti J, Gådin JR, Bäcklund A, de Faire U, Gertow K, Giral P, Goel A, Humphries SE, Kurl S, Langenberg C, Lannfelt LL, Lind L, Lindgren CCM, Mannarino E, Mook-Kanamori DO, Morris AP, de Mutsert R, Rauramaa R, Saliba-Gustafsson P, Sennblad B, Smit AJ, Syvänen AC, Tremoli E, Veglia F, Zethelius B, Björck HM, Eriksson JG, Hofman A, Franco OH, Watkins H, Jukema JW, Florez JC, Wareham NJ, Meigs JB, Ingelsson E, Baldassarre D, Hamsten A; IMPROVE study group. Strawbridge RJ, et al. Among authors: humphries se. Atherosclerosis. 2017 Nov;266:196-204. doi: 10.1016/j.atherosclerosis.2017.09.031. Epub 2017 Sep 28. Atherosclerosis. 2017. PMID: 29040868 Free PMC article.
Factor VII Arg/Gln353 polymorphism determines factor VII coagulant activity in patients with myocardial infarction (MI) and control subjects in Belfast and in France but is not a strong indicator of MI risk in the ECTIM study.
Lane A, Green F, Scarabin PY, Nicaud V, Bara L, Humphries S, Evans A, Luc G, Cambou JP, Arveiler D, Cambien F. Lane A, et al. Atherosclerosis. 1996 Jan 5;119(1):119-27. doi: 10.1016/0021-9150(95)05638-6. Atherosclerosis. 1996. PMID: 8929253
A novel functional polymorphism in the PECAM-1 gene (53G>A) is associated with progression of atherosclerosis in the LOCAT and REGRESS studies.
Elrayess MA, Webb KE, Flavell DM, Syvänne M, Taskinen MR, Frick MH, Nieminen MS, Kesäniemi YA, Pasternack A, Jukema JW, Kastelein JJ, Zwinderman AH, Humphries SE. Elrayess MA, et al. Among authors: humphries se. Atherosclerosis. 2003 May;168(1):131-8. doi: 10.1016/s0021-9150(03)00089-3. Atherosclerosis. 2003. PMID: 12732396
Influence of factor VII gene polymorphisms and environmental factors on plasma coagulation factor VII concentrations in middle-aged women with and without manifest coronary heart disease.
Eriksson-Berg M, Deguchi H, Hawe E, Scanavini D, Orth-Gomér K, Schenck-Gustafsson K, Humphries SE, Silveira A, Hamsten A. Eriksson-Berg M, et al. Among authors: humphries se. Thromb Haemost. 2005 Feb;93(2):351-8. doi: 10.1160/TH04-09-0616. Thromb Haemost. 2005. PMID: 15711754
The molecular basis of familial hypercholesterolaemia in Turkish patients.
Sözen MM, Whittall R, Oner C, Tokatli A, Kalkanoğlu HS, Dursun A, Coşkun T, Oner R, Humphries SE. Sözen MM, et al. Among authors: humphries se. Atherosclerosis. 2005 May;180(1):63-71. doi: 10.1016/j.atherosclerosis.2004.12.042. Atherosclerosis. 2005. PMID: 15823276
843 results