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Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation.
Strawbridge RJ, Silveira A, Hoed MD, Gustafsson S, Luan J, Rybin D, Dupuis J, Li-Gao R, Kavousi M, Dehghan A, Haljas K, Lahti J, Gådin JR, Bäcklund A, de Faire U, Gertow K, Giral P, Goel A, Humphries SE, Kurl S, Langenberg C, Lannfelt LL, Lind L, Lindgren CCM, Mannarino E, Mook-Kanamori DO, Morris AP, de Mutsert R, Rauramaa R, Saliba-Gustafsson P, Sennblad B, Smit AJ, Syvänen AC, Tremoli E, Veglia F, Zethelius B, Björck HM, Eriksson JG, Hofman A, Franco OH, Watkins H, Jukema JW, Florez JC, Wareham NJ, Meigs JB, Ingelsson E, Baldassarre D, Hamsten A; IMPROVE study group. Strawbridge RJ, et al. Among authors: de faire u, de mutsert r. Atherosclerosis. 2017 Nov;266:196-204. doi: 10.1016/j.atherosclerosis.2017.09.031. Epub 2017 Sep 28. Atherosclerosis. 2017. PMID: 29040868 Free PMC article.
Abdominal adiposity largely explains associations between insulin resistance, hyperglycemia and subclinical atherosclerosis: the NEO study.
Gast KB, Smit JW, den Heijer M, Middeldorp S, Rippe RC, le Cessie S, de Koning EJ, Jukema JW, Rabelink TJ, de Roos A, Rosendaal FR, de Mutsert R; NEO study group. Gast KB, et al. Among authors: de roos a, de mutsert r, de koning ej. Atherosclerosis. 2013 Aug;229(2):423-9. doi: 10.1016/j.atherosclerosis.2013.05.021. Epub 2013 Jun 1. Atherosclerosis. 2013. PMID: 23880198 Free article.
Body fat, especially visceral fat, is associated with electrocardiographic measures of sympathetic activation.
Hillebrand S, de Mutsert R, Christen T, Maan AC, Jukema JW, Lamb HJ, de Roos A, Rosendaal FR, den Heijer M, Swenne CA; NEO Study Group. Hillebrand S, et al. Among authors: de roos a, de mutsert r. Obesity (Silver Spring). 2014 Jun;22(6):1553-9. doi: 10.1002/oby.20709. Epub 2014 Feb 18. Obesity (Silver Spring). 2014. PMID: 24458875 Free article.
Type 2 diabetes is associated with postprandial amino acid measures.
Mook-Kanamori DO, de Mutsert R, Rensen PC, Prehn C, Adamski J, den Heijer M, le Cessie S, Suhre K, Rosendaal FR, van Dijk KW. Mook-Kanamori DO, et al. Among authors: de mutsert r. Arch Biochem Biophys. 2016 Jan 1;589:138-44. doi: 10.1016/j.abb.2015.08.003. Epub 2015 Aug 10. Arch Biochem Biophys. 2016. PMID: 26271442 Clinical Trial.
Association between Hepatic Triglyceride Content and Left Ventricular Diastolic Function in a Population-based Cohort: The Netherlands Epidemiology of Obesity Study.
Widya RL, de Mutsert R, den Heijer M, le Cessie S, Rosendaal FR, Jukema JW, Smit JW, de Roos A, Lamb HJ; NEO Study Group. Widya RL, et al. Among authors: de roos a, de mutsert r. Radiology. 2016 May;279(2):443-50. doi: 10.1148/radiol.2015150035. Epub 2016 Jan 26. Radiology. 2016. PMID: 26812225
221 results