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Page 1
Mammalian γ2 AMPK regulates intrinsic heart rate.
Yavari A, Bellahcene M, Bucchi A, Sirenko S, Pinter K, Herring N, Jung JJ, Tarasov KV, Sharpe EJ, Wolfien M, Czibik G, Steeples V, Ghaffari S, Nguyen C, Stockenhuber A, Clair JRS, Rimmbach C, Okamoto Y, Yang D, Wang M, Ziman BD, Moen JM, Riordon DR, Ramirez C, Paina M, Lee J, Zhang J, Ahmet I, Matt MG, Tarasova YS, Baban D, Sahgal N, Lockstone H, Puliyadi R, de Bono J, Siggs OM, Gomes J, Muskett H, Maguire ML, Beglov Y, Kelly M, Dos Santos PPN, Bright NJ, Woods A, Gehmlich K, Isackson H, Douglas G, Ferguson DJP, Schneider JE, Tinker A, Wolkenhauer O, Channon KM, Cornall RJ, Sternick EB, Paterson DJ, Redwood CS, Carling D, Proenza C, David R, Baruscotti M, DiFrancesco D, Lakatta EG, Watkins H, Ashrafian H. Yavari A, et al. Among authors: ashrafian h. Nat Commun. 2017 Nov 2;8(1):1258. doi: 10.1038/s41467-017-01342-5. Nat Commun. 2017. PMID: 29097735 Free PMC article.
Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity.
Siggs OM, Stockenhuber A, Deobagkar-Lele M, Bull KR, Crockford TL, Kingston BL, Crawford G, Anzilotti C, Steeples V, Ghaffari S, Czibik G, Bellahcene M, Watkins H, Ashrafian H, Davies B, Woods A, Carling D, Yavari A, Beutler B, Cornall RJ. Siggs OM, et al. Among authors: ashrafian h. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3706-15. doi: 10.1073/pnas.1607592113. Epub 2016 Jun 14. Proc Natl Acad Sci U S A. 2016. PMID: 27303042 Free PMC article.
Genetic cardiomyopathies causing heart failure.
Cahill TJ, Ashrafian H, Watkins H. Cahill TJ, et al. Among authors: ashrafian h. Circ Res. 2013 Aug 30;113(6):660-75. doi: 10.1161/CIRCRESAHA.113.300282. Circ Res. 2013. PMID: 23989711 Review.
Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.
Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martínez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Tóth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H. Yavari A, et al. Among authors: ashrafian h. Cell Metab. 2016 May 10;23(5):821-36. doi: 10.1016/j.cmet.2016.04.003. Epub 2016 Apr 28. Cell Metab. 2016. PMID: 27133129 Free PMC article.
Inherited cardiomyopathies.
Watkins H, Ashrafian H, Redwood C. Watkins H, et al. Among authors: ashrafian h. N Engl J Med. 2011 Apr 28;364(17):1643-56. doi: 10.1056/NEJMra0902923. N Engl J Med. 2011. PMID: 21524215 Free article. Review. No abstract available.
Citric acid cycle intermediates in cardioprotection.
Czibik G, Steeples V, Yavari A, Ashrafian H. Czibik G, et al. Among authors: ashrafian h. Circ Cardiovasc Genet. 2014 Oct;7(5):711-9. doi: 10.1161/CIRCGENETICS.114.000220. Circ Cardiovasc Genet. 2014. PMID: 25518044 Review.
539 results